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Re: Obstetric cholestasisFrom: Harvey S. Marchbein, M.D. (anonymous@obgyn.net)Wed, 29 Dec 1999 10:19:05 -0600 (CST)
At Tue, 28 Dec 1999, caroline wrote: > >I am 41 years old and 34 weeks pregnant with a so-far uneventful, normal >pregnancy. About 3 weeks ago I began experiencing allover itching with >no rash. My doctor ordered blood tests to check on liver function but >due to lab mess-ups (three blood tests have now been drawn) I still >don't have the results. > >I'm obviously worried and did some research - and my symptoms seem to be >consistent with obstetric cholestasis, being a problem with the liver >that can develop during the third trimester resulting in excessive bile >salts in the blood - thus, the itching (which is driving me CRAZY!). > >The research I've done indicates that (1) there's no real treatment for >this (although there is treatment for the itching) other than delivery >and, more importantly (2) there seems to be some connection between this >and stillbirth. My reading recommends delivery before 38 weeks to >reduce the chance of problems. > >My doctors have told me that there's no proven connection between OC and >stillbirths - any thoughts on this? I don't want to be overreacting. >However - I want to take every precaution possible. I'm not thrilled >about the idea of induction or cesaerian, but the alternative is too >horrible to even contemplate. > >I appreciate the insight of any doctors who have experience or knowledge >about this - there is not much information out there and what there is >seems to come from the UK. > >Thanks so much - sorry this is so long. > >Caroline I'm aware of no association with stillborns and did a literature search on Medline and came up empty. A consultatio with a fetal meaternal medicine specialist may reveal lesser known studies that support one side or the other.
-- Harvey S. Marchbein, M.D. FACOG, FACS Great Neck, New York
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