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Re: Attn Dr Marchbein Re: progesterone & maintaining pregnancyFrom: Harvey S. Marchbein, M.D. (anonymous@obgyn.net)Mon, 27 Dec 1999 19:28:21 -0600 (CST)
At Sun, 26 Dec 1999, Jas wrote: > >Hi Dr Marchbien > >Now I am intigued by your reply and explaination of progesterone's role >in pg later on. If I understand correctly what you are saying about >progesterone then those of us who deliver preterm may have a sudden >premature drop of our progesterone level too early? One possibility but then we have to figure out why. Subclinical infection? Less progesterone receptors (not less progesterone but lower ability to respond to it since receptors help get the work done) in the uterus and if so, why? Let's not leave out incompetent cervix (unrelated to progesterone), multiple births (posibly related to stretching of the uterus and "hitting it's limits") and others that will come to me later, I'm sure.
>What I was wondering I've never seen it but I'm sure there's an article somewhere. The problem is even if you know the amounts, we have no way to change it in 1999/2000 after the first trimester.
>Can Good question. Wish the answer was known.
>In my last pg I used progesterone supplements early on until week 11. You don't think too much. We probably know too little but hope springs eternal for the future. ;-)
-- Harvey S. Marchbein, M.D. FACOG, FACS Great Neck, New York
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