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Re: Clomid and PregnancyFrom: Harvey S. Marchbein, M.D. (anonymous@obgyn.net)Sun, 19 Dec 1999 10:27:30 -0600 (CST)
At Sat, 18 Dec 1999, AnnMarie wrote: > >>Dr HM wrote: >> >>Are you ovulating on 50mg? If not, go to 100mg. If very overweight or >>if you fit the PCO criteria (mentioned many times in the archives), the >>use of Glucophage enhances the effectiveness of Clomid. The pregnancy >>rate goes from 40% to over 80%. > >That's new to me! Very interesting! How does the Glucophage work that way? > >AM It is felt that Clomid is treating the end result of another problem. With insulin resistance (the primary problem), it goes like a domino effect to increase androgens (male hormones) and that, in turn, throws off ovulation. Glucophage works against insulin resisitance. This cascade doesn't occur in everyone who doesn't ovulate but the statistics are impressive.
-- Harvey S. Marchbein, M.D. FACOG, FACS Great Neck, New York
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