 |
 |
 |
|
|
|||
|
|
||||
|
||||
|
Re: Anti -E Positive Test Result-Ann Marie/Paige etc.From: Christine (anonymous@obgyn.net)Fri, 17 Dec 1999 08:19:34 -0600 (CST)
At Thu, 16 Dec 1999, AnnMarie wrote: > >At Thu, 16 Dec 1999, Harvey S. Marchbein, M.D. wrote: >> >>FOUND IT!!!!!!!!! >> >>It was on the Women's Health Forum >>http://forums.obgyn.net/womens-health/WHF.9912/0005.html >> >>If this doesn't help, let me know. :-) >> >HEY! I *almost* found it first! I got to the original thread then missed >that reply. Like you said, server problems. GRRRRRR! > >I reread that post and all those letters sound like Dr. Seuss to me. >Big 'E', little 'e'. What begins with E? But seriously, now that I >reread it I can probably rule out that the antibody I tested postive for >in my first pregnancy was E---I am Rh positive. Hmmmmm, maybe I should >read that thing again. I know I'm missing something. Has anyone taken >notes off a post before? Now I'm starting to miss school and I haven't >been in college since 1991. I'd say 1992 but it was a joyride for me >that year while I awaited my turn in the Army. I'm rambling. > >AM Hi! I saw Paige's post and, although I understand how anti-E forms, I didn't feel I could add anything to the discussion about a positive titer in pregnancy. IMHO a titer of 1:2 is quite weak, but I really don't know too much about the clinical applications. How quickly does it rise for example when a mother with anti-E has another E positive fetus? Ann Marie, your antibody could have been anti-E even if you are RH positive. According to my chart, about 50 % of people who are RH positive are negative for big E. Therefore, if you carried a baby that had the big E antigen (which is very possible) you could be sensitized and form anti-E. In the case of blood transfusion, if you type as RH positive, then you receive RH positive blood, sometimes RH negative, depending on the blood supply. (Rh negative patients receive only RH negative blood). That blood could be positive or negative for E and if positive, this would be another way someone could be sensitized and form anti-E. They would only test the units you were to receive for big E if you already had anti-E in your serum. E, e, C, c and D are all part of the RH system (yes, it does sound like Dr Suess!) but when you speak of being RH positive or negative you are referring only to the D antigen. You can test a person for the presence of the other antigens (E,e,C,c) but this is not routinely done. I am interested in the clinical applications myself if anyone has the answers. What would be considered a significant rise in titer and at what point in pregnancy would this happen? I do know the worst case scenario, that is that the baby has to be transfused at birth but I don't think this happens very often. Chris S.
|
| |
Women's Insurance Checklist from Auto Insurance Quote home | medical professionals | women | industry | forums | internationale-mail | about us | advertising | our sponsors | contact us | disclaimer | This information is provided for educational purposes only. Please read the disclaimer. ©1996-2008, all rights reserved. Do not reproduce without permission of MediSpecialty.com |
![[ Pregnancy & Birth Forum ]](/pregnancy-birth/pnb_forum_L.gif)