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Re: Rhogam injection during PregnancyFrom: Harvey S. Marchbein, M.D. (anonymous@obgyn.net)Sun, 21 Nov 1999 14:16:29 -0600 (CST)
At Sun, 21 Nov 1999, Christine wrote: > >Hi! > >I just read the post about RH incompatibility and miscarriage and I >realized that they must now be giving Rhogam during pregnancy (to RH >negative mothers) as well as after delivery of an RH positive infant to >an RH negative woman (and also miscarriage in an RH negative woman) I >can see where they could not risk sensitization from miscarriage, but is >the chance of sensitization during pregnancy a great enough risk to >justify using Rhogam when the blood type of the fetus is unknown? Absolutely. A Canadian study several years ago showed a 1-2% sensitization rate when RhoGam was given only after delivery. Adding the shot between 28 and 32 weeks drops this to near zero. You just have to see one sensitized pregnancy and the amazing and heroic efforts necessary to save such a pregnancy (not to mention the emotional and financial toll on the family) to see the worth in an "extra" shot. Worth it's weight in gold? And there's no down side. If the baby's Rh negative, no harm.
>Another question-the person who posted mentioned that her husband was RH Another can of worms and your point is well taken. I presume that a ptient won't lie to me about the paternity issue and so far, I haven't been disappointed (to my knowledge). Haven't had any sensitized babies yet. Thank G-d.
-- Harvey S. Marchbein, M.D. FACOG, FACS Great Neck, New York
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