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Re: Auto Immunue Progesterone DermatitisFrom: Sara (anonymous@obgyn.net)Fri, 10 Sep 1999 17:10:22 -0500 (CDT)
At Fri, 10 Sep 1999, Harvey S. Marchbein, M.D. wrote: > >Just because I've never heard of it doesn't mean it doesn't exist. the >only thing I'm confused about is the fact that you had it for one week >only in your pregnancy and then it cleared up. The progesterone levels >in pregnancy rise from beginning to end. Can't figure this one out. >I agree with your confusion Dr. Marchein. I can tell you that I also tend to suffer from basic hay fever and that has always cleared up during pregnancy as well. Perhaps any "allergic" type of reaction clears up for me during pregnancy even though pregnancy itself generates one of the very things that cause a problem ???? I received a reply from Mary Shoup as well. She had not heard of this condition either and researched MEDLINE on the net and found interesting info. I then searched the web and came up with several sites to explore. I now know that I should have had a skin prick test of progesterone to help confirm the diagnosis and I have to tell you I never had that. I am not sure I even have this disorder - it appears that skin manifestations can come from many sources and the progesterone prick is critical to the diagnostic procedure. Thanks for you input. I truly appreciate it. >Harvey Marchein, M.D. > >At Tue, 7 Sep 1999, Jo wrote: >> >>Has anyone ever heard of this? Had been on pill for about 7 years when I >>began to get a horrible rash, which would occur in different parts of my >>body. Rash would itch terribly, resemble something similar to mosquito >>bites. No fluids in the bumps. I'd scratch until they become quite >>irritated and usually scab over. Then they'd heal but my skin would be >>"stained" where rash had been. This stain would remain a few months and >>gradually go away. Went to dermatologist. Never could diagnos. Took >>biopsy and result showed a drug interaction caused the problem. Asked >>if pill could cause it, told no. Treated with Prednesone which really >>helped. AS soon as prednesone treatment stoped, rash reappeared. >>Suffered terribly for years. Went to other doctors. No help found. >>Took myself off pill and rash just about cleared up, only to surface >>each time my period was due. Lived with it for a few years. Had an >>especially bad bout with the rash one month and since I'd recently moved >>to another state I sought out a new dermatologist. He diagnosed my >>condition as "Autoimmune Progesterone Dermatitis". He claims this was a >>condition that was due to having been on the pill. Even though I had >>now been off the pill for three years, somehow my natural hormones were >>STILL affected by having been on the pill. He claims he came across >>this condition in a medical journal and that there was not a lot of >>info. available. He had a report which included 7 case histories. >>These women had the rash (even after having gone off the pill) and >>although they were able to conceive all miscarried early in pregnancy. >> >>I still get this rash and have miscarried four times. I did have a >>successful pregnancy and a healthy child resulted. While I was >>pregnant, all five times, the rash was horrible in the first week or so >>of pregnancy and then disappeared COMPLETELY. Following the >>miscarriages and the delivery of my one child, that darned rash returned >>with each monthly cycle. >> >>No OBYGN who I have ever talked to has heard of this condidtion. Any >>one out there ever heard of it? I'd like to know if this condition truly >>exists as and if my dermatologist was correct in his diagnosis. Sorry >>so long, but I needed to explain it fully and that took space. Thanks >>for any information you may have. > >-- >Harvey S. Marchbein, M.D. FACOG, FACS >Great Neck, New York >http://www.obgyn.net/states/bios/marchbein.htm >http://www.obgyn.net/women/advisors/harveym.htm > >**Note: Opinions expressed here are for educational purposes only >and, as such, do not constitute a physician-patient relationship. >This information is not intended to supplant the need for you to >consult with your physician prior to choosing therapeutic options >and/or interventions. > >**Private emails cannot be entertained due to time constraints, >consequently no private emails will receive a response. > >**Thank you for your understanding ;-) >
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