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Re: Progesterone during pregnancy?From: Marcia (anonymous@obgyn.net)Fri, 10 Sep 1999 15:35:50 -0500 (CDT)
I used natural progesterone during my last pregnancy. I believe that it helped me to maintain the pregnancy. The suppositories that I used were prescribed by an obstetrician and made in the hospital pharmacy (by hand).At Fri, 10 Sep 1999, anonymous@obgyn.net wrote: > >At Mon, 22 Mar 1999, Tina wrote: >> >>Hello >>I am not a medical doctor but I have a Ph.D. in biochemistry. I am >>currently in my 31st week. During my first week, I spotted and when >>checked, discovered that my progesterone was borderline. My OB >>prescribed Protmetrium for me (I can't remember the dose but it amounted >>to 2 tablets/day). I read the product insert and also was scared but >>the same line (not recommended for pregnancy...). I called Solvay >>Pharmaceuticals who is the producer of Prometrium (if I recall >>correctly). Anyway, I spoke with one of their Ph.D.s who worked on >>Prometrium. She told me there have been isolated cases of children born >>with birth defects whose mothers had used Prometrium. The birth defects >>were one case of cleft pallate (sp?), a couple of cases of heart >>problems. However, there was no evidence to indicate these problems >>were directly caused by the progesterone and were merely coincidental. >>However, because they occurred and these mothers had taken Prometrium, >>they were required to use this disclaimer in the product insert. She >>went on to tell me the statistics (although I can't remember them) on >>the number of "normal" babies born to mothers taking prometrium. To me, >>there was a greater risk of losing the baby than having birth defects >>caused by supplemental progesterone. I have had 2 u/s and my babies >>heart looks perfect. Additionally, I my best friend was on progesterone >>suppositories with her second child (after miscarrying her first - which >>was attributed to progesterone deficiency). Her now 4 year old daughter >>is very intelligent and healthy. I know, however, that many OBs state >>that their is no proven relationship between supplementing with >>progesterone and not-miscarrying. Incidentally, I had swithched OBs >>shortly after initiating the Prometrium. The new OB told me that as far >>as he was concered my progesterone was not too low but that if taking it >>eased my mind then to take it as there was no risk to the baby. I ended >>up taking only 1 pill per day which may have been physically >>inconsequential but mentally reassuring at the time. Sorry this is so >>long. >> >>Tina >> >>At Sun, 21 Mar 1999, Monica wrote: >>> >>>I was wondering how safe progesterone (Prometrium specifically) is to >>>use during pregnancy? I know a woman whose daughter was born with heart >>>defects attributed to the use of prosterone during her pregnancy. The >>>insert in the box specifically says "Do not use Prometrium if you are >>>pregnant or nursing." Why would my OB prescribe this for my pregnancy if >>>it is unsafe to use while pregnant? This is my ninth pregnancy, and I >>>have two children. My last miscarriage was in October 98, at 10 weeks >>>(all my losses were 6-7 weeks developed). I am extremely frightened of >>>losing another child, so I accepted the progesterone prescription from >>>my doctor, but I am also afraid of causing the baby and harm. >>>How long is progesterone usually used in a pregnancy? The package insert >>>says that if you stop taking it you will shed the lining of your uterus. >>>Could it cause a miscarriage if I stop taking it? >>>I have also learned that natural progesterone is less harmful than >>>synthetic progesterone. Is "Prometrium" a natural or synthetic >>>progesterone supplement? >>>I understand that it is almost impossible to diagnose problems online, >>>but I would appreciate any statistics and information you can give me. >>> >>>Thank you in advance for your help. >>> >>>-- >>>Monica >>> >>-- >>
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