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Re: Acute ChroioamniotisFrom: anonymous@obgyn.netWed, 14 Jul 1999 21:17:40 -0500 (CDT)
At Wed, 14 Jul 1999, Jan wrote: > >My daughter gave birth to a stillborn son(21 weeks). The microscopic >diagnosis reads"115 gm, placenta with marked acute chorioamnionitis and >thromobtic material. Focal infarction present, no atypia identified." >What does this mean in laymen's term? >Also, is there a way to diagnose this in order to prevent a stillborn >birth? >Jan acute chorioamnionitis= obvious evidence of severe inflammation associated with infection thrombotic material= blood clot focal infarction= one or more small areas that lost their blood supply sometime prior to death (this is very common, and is especially associated with infection) no atypia= the cells observed under the microscope were normal in general configuration and type There is not really anyway to diagnose an infection of the placenta and membranes without getting a sample of the amniotic fluid. There are other clinical indicators sometimes, such as maternal fever, abdominal tenderness and so forth. Unfortunately, there is not very much that can be done to treat this problem. Generally, this is a problem of late pregnancy, and so we just deliver the baby, but at 21 weeks, even if you were to make the diagnosis, delivery is not going to result in a living baby. Antibiotics are not very effective.
-- William D. McIntosh, MD
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