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chromosomal rearrangement & hereditary miscarriages

From: Mary (anonymous@obgyn.net)
Tue, 2 Mar 1999 10:31:37 -0600 (CST)


Hello. My first pregnancy ended due to a blighted ovum a month ago. Yesterday when I went to see my OB for a post-partum, she said that, despite the random nature of blighted ovums and the fact that 25% of first pregnancies end in miscarriage, I may want to think about a (expensive) test for chromosomal rearrangement (between my husband and me) which would prevent me from carrying our pregnancy to term. She mentioned the test because yesterday I noted my family history (my mother had three miscarriages and my mother-in-law had two miscarriages), but said she would probably only order the test after two or three miscarriages. (My OB is a university physician and may be more likely to mention the test since her research pertains to chromosomes.)

So has anyone ever heard of chromosomal rearrangement or what it means in terms of my odds of carrying our pregnancy to term? Is the tendency to miscarry passed down from one generation to the next?

Thank you.






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