Re: miscarriage and immune system

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Hi...there seems to be a lot of talk lately on this forum (including a response to my post) on the the immune system and its role in miscarriage. The Dr. responded that my miscarriage at 6w1d could possibly be because of immune reasons. I do have 2 fairly recent (since 2000) healty children born to me, so I know I can carry a baby to term. But, I have had 1 chemical pregnancy (5 weeks) and 1 the miscarraige stated above in the last 7 or so months.

My question is, can someone develop an immune problem at any point in their reproductive years? In other words, is my body just now after 2 healthy pregnancies rejecting the embryo? The Dr. mentioned the chemical pregnancy was probably for chromosomal reasons but the 2nd could possibly have been because of immune reasons. Specifically, what type of immune problems would cause a miscarriage? And can they just "pop up" all of a sudden?

I am just curious. Should I be insisting on an immune workup in my case?

Thanks in advance!

Dear Anonymous, Yes, you can develop immune problems at any point in your reproductive life, or be asymptotic, then have a sub-clinical problem manifest. Many clues may be subtle and less assessable when non-pregnant. The immune system is dynamic and affected by many influences including but not limited to common things e.g.. diet, stress, illness, medications and genetics. The fact that you have had two healthy children shows that you have that potential, if you have evidence of impaired immune system, the prognosis is good for treatment, nor is it necessarily, "rejecting the embryo". There's not enough room to explain, try a search with "antibodies recurrent miscarriage" and you will find many sites devoted to this discussion. I would ask for some tests since you did have two healthy babies then 2recurrent M/C, it's even possible that there were some clues during your successful pregnancies that were clues, clotting/bleeding, low-birthweight, thyroid, aged placenta, you may want to obtain copies of your medical records, you have a right to these. The links previously provided give suggestions for a workup take it to your doctor and go from there or ask for a referral. Marie

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