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Re: Miscarriage and Misoprostol Not Helping

From: Asem Anwar Moussa MD (anonymous@obgyn.net)
Sun, 23 Feb 2003 22:49:59 -0600 (CST)

At Sun, 23 Feb 2003, Kate wrote: >
>Hi there.
>
>I just learned on Thursday (2/20) that my pregnancy was no longer
>viable. At 7 weeks, 2 days, we saw a good heartbeat of 140 and the
>embryo measured to date based on LMP. On Thursday I was 9 weeks, 5 days
>and was so shocked to learn there was no longer a heartbeat. This is my
>second consecutive miscarriage and I'm so frustrated and confused.
>
>I should add that I do have a unicornate uterus. As a result, I see a
>group of doctors at a very reputable high-risk clinic and the doctors
>there do not feel that my uterus has contributed to the problem this
>early in the game. I conceived spontaneously, no fertility treatments
>at all. This is my second pregnancy within a year.
>
>I don't want another D&C so my doctor prescribed Misoprostol (400 mcg
>every 12 hours for 4 doses). I finished the last dose this morning and
>have had very little bleeding and no cramping whatsoever. I feel like
>it hasn't even helped at all (except for giving me terrible diarrhea!).
>How long does it normally take for Misoprostol to work?
>
>Just a couple of more questions...
>
>Why would the embryo just suddenly die off, especially after it appeared
>to be thriving?
>
>My doctor wants to verify my progesterone levels and also test for
>antibodies that my cause clotting problems. Are there any other tests
>that you doctors would recommend at this stage?
>
>I greatly appreciate any insight or advice that anyone can offer!
>
>Thank you so much,
>
>~ Kate

1-Misoprostol can be repeated,but if it fails,you better do a D/C. 2-Many other causes would lead to miscarraige&death of the fetus after it appeared to be thriving like the antiphosolipid syndrome,chromosomal,hormonal,etc. 3-May be added to that a genetic counseling&investigations. 

--
Dr:Asem Moussa MD
Prof.of OB/GYN.
Alazhar School of Medicine.
Cairo-Egypt
This is for teaching purposes



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