PREGNANCY-BIRTH Messages for February, 2003: Re: Procardia/Nifedipine

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Re: Procardia/Nifedipine

From: samir fouad Aziz MD (anonymous@obgyn.net)
Mon, 3 Feb 2003 16:42:20 -0600 (CST)

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In reply to: Mary: "Procardia/Nifedipine"
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Reply: Mary: "Re: Procardia/Nifedipine"

At Mon, 3 Feb 2003, Mary wrote: >
>I stumbled upon a post here questioning Procardia usage during
>pregnancy. I cannot seem to post to that particular thread so I
>apologize first.
>
>Now, the reason I am posting is because, 1. I too, was wondering if
>there were any adverse effects to the baby from Nifedipine usage.
>2. I am wondering why, if this is in use, does it not have FDA approval
>for the use of preterm labor/anti-contraction situations? (and I know
>not all information on the web is perfect and true BUT...)
>
>I guess what I'm trying to drag out of an educated medical professional
>is: Would I be safer using Ritoden (I think that's the correct spelling)
>that IS FDA approved for the specific use of anti-contraction or should
>I honestly feel comfortable using a 'new' drug that isn't approved for
>the use it is prescribed to me for (preterm labor/irritable uterus)?
>AND, if the answer IS to be safer with Ritoden, as a patient, are my
>rights as such that I can request that I be placed on that rather than
>Procardia?
>I was informed that Procardia is for usage on smooth muscle tissue
>(heart) and that the uterus is a smooth muscle so that's why the
>presciption of it. Anyway, thanks and I look forward to hearing what
>you have to say on the subject.
>
>I thank you for reading and I'll be researching both medications on my
>own but just wanted an HONEST opinion on the drug itself.

Nifedipine is a caclicum channel blocker and used for treatment of hypertension,its use as inhibitor of uterine contraction is not prcaticed widely, since its effectivness in preventing preterm labour is not fully established,its use usually started late in pregnancy after the period of organogensis and so far no deletrious effects seen with its use wether as a hpotensive agent or as inhibitor for uterine contractions,but it may reduce the mother's blood pressure to the extent it could affect the blood flow the baby with decrease oxygenation of the baby, so it should be monitored carefully >
>*Sites referenced/researched:
>http://www.adrugrecall.com/procardia/procardia.html
>http://www.healthsquare.com/newrx/pro1352.htm
>http://www.accessmednet.com/
>http://www.rxlist.com/cgi/generic2/nifedip_wcp.htm
>http://www.pfizer.com/download/uspi_procardia.pdf <--acrobat reader
>needed
>http://www.ecureme.com/eMyHealth/data/Nifedipine_(Procardia_XL).asp

--
SAmir Fouad Aziz MD
Assist Professor OB.Gyn
Director Gyn.oncology
Al-Azhar University-Egypt
Editorial advisor OBgyn.net(P&B,Gyn.Oncology)
Consultant Editor the contemporary Who's Who
This is for teaching purposes only

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