Re: 2 m/c in a row for NORMAL couple: bad luck or sth else?
From: james wang, M.D. (anonymous@obgyn.net)
Mon, 18 Mar 2002 21:38:15 -0600 (CST)
Most early miscarriages are abnormal chromosomally. this is due to the
complex nature of genetics and the vast number of chromosomes in the
human genome. Normal chromsomal studies in both partners is a good
indication of bad luck.
At Mon, 18 Mar 2002, anonymous@obgyn.net wrote:
>
>One Dr. on this forum said that 1 out of 100 Normal couple will have 2
>m/c in a row.
>1. Then how common is that for a NORMAL couple to have two m/c in a row
>due to chromosomal abnormality?
>We had 2 first trimester m/c at the age of 30 (DH 31) with the second
>being trisomy 22 and the first unknown and DH and I are normal
>genetically.
>2. I don't know whether the first one was due to a chromosomal problem
>also or not but if it is (since most early m/c is caused by chromosomal
>issue) then why it could happen twice in a row since both of us do not
>have numerical or structural chromosome problem from the bloodwork?
>3. We both tested for everything which would cause m/c and both normal.
>If the first one was not due to chromosome problem then what else could
>cause the abnormal development of the embryo?
>4. Or did we just have back luck?
>5. And how common is that chromosome defect is in the ovary or testes
>if not from the bloodwork?
>Can you please shed some light on this? Thanks a lot!
--
James Wang, M.D
Assitant Clinical Prof.
Tufts University School of Medicine
Note: opinions expressed here are for educational purposes
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