Re: Q for Maggie the med student Re: Grapefruit juice?
From: Harvey S. Marchbein, M.D. (anonymous@obgyn.net)
Sun, 10 Mar 2002 17:37:37 -0600 (CST)
Who's going to do thye randomized control trial, double blind?
Dr. M
At Sun, 10 Mar 2002, Jane wrote:
>
>At Sun, 10 Mar 2002, Maggie, wrote:
>>
>>At Sat, 9 Mar 2002, Kristina wrote:
>>>
>>>I've heard that drinking grapefruit juice will help you conceive. How
>>>does this work, and is it true? When do I have to drink it, and how
>>>much? What exactly does it do? Has anyone out there had luck with this
>>>method?
>>
>>Dear Kristina,
>>
>>Not true.
>
>Maggie,
>
>The latest gossip on the fertility boards is that grapefruit juice
>increases cervical mucus in both quantity and quality (more, thinner,
>stretchier). I admit it - I tried it myself and it had a marked effect
>(my husband, unaware of my juice-drinking, commented on the increased
>CM, FWIW.). So I did some research and found a number of articles
>discussing the fact that GFJ does apparently inhibit the metabolism of
>exogenous estrogens, resulting in increased blood levels in women on
>estrogen supplementation who take grapefruit juice. I assume this is
>similar to other GFJ-drug interactions and involves the P450 system or
>other similar hepatic pathway. So, wouldn't it be possible that GFJ
>could also inhibit breakdown of endogenous estrogens? That would, IMO,
>be one explanation for the anecdotal reports of increased CM with large
>amounts of GFJ. Maybe this would be a good research project for you :)
>
>-Jane,VMD
--
Harvey S. Marchbein, M.D. FACOG, FACS
Great Neck, New York
**Note: Opinions expressed here are for educational purposes only
and, as such, do not constitute a physician-patient relationship.
This information is not intended to supplant the need for you to
consult with your physician prior to choosing therapeutic options
and/or interventions.
**Private emails cannot be entertained due to time constraints,
consequently no private emails will receive a response.
**Thank you for your understanding.
Please be aware that all e-mail on this forum is archived and can be viewed at
http://forums.obgyn.net/womens-health,
http://forums.obgyn.net/pregnancy-birth or
http://forums.obgyn.net/young-women
and is accessible to anybody on the
internet including internet search engines. This should be taken into
consideration before sending postings of a personal or confidential nature.
![[ Pregnancy & Birth Forum ]](/pregnancy-birth/pnb_forum_L.gif)