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Hyperinsulinism and miscarriagesFrom: Heather (anonymous@obgyn.net)Mon, 31 Dec 2001 10:23:42 -0600 (CST)
I don't know that two instances of something makes a pattern, but I'm REALLY concerned. I've been diagnosed with hyperinsulinism after a long fight to find the cause of my chronic fatigue and spuradic, excessive (up to 70 pounds in 5-6 months) weight gain. A new OB/GYN immediately pegged it as hyperinsulinism and put me on Glucophage (metformin). My fasting insulin level was a 22. The fatigue immediately disappeared and the weight stopped accelerating. My problem is that I've noticed that I'm ovulating incredibly late in my cycles and when I last conceived (six months ago), the embryo appeared to have stopped developing or only developed to a 3-week state. My initial hcG levels were very low and sluggish to increase. I miscarried at the 6th week of gestation and I was age 29. Prior to that pregnancy, I had been pregnant twice before and made it to the 10th and 11th week before aborting. The first time I was 19 and the second time was after a date-rape when I was 25. By the first pregnancy I had already been suffering signs of hyperinsulinism with the excessive and spuradic weight gain and had been misdiagnosed with hypoglycemia. I have only been using the Glucophage for the last year, but I've gone for an entire 4-6 weeks here and there without taking it. After my miscarriage, my cycles got shorter (26 days vs. my normal 30+/-) and dead accurate. I had three full cycles before conceiving again and I'm now pregnant. I also happened to be using an ovulation monitor (urine test) and know that I ovulated late in my cycle. Again, my hcG levels are low (196.8 at an estimated 3rd week of gestation. My concern is that I'm going to miscarry again...
-- Is there any potential relationship between the hyperinsulinism, the late ovulation and the miscarriage? Is it even REMOTELY possible that my husband's sperm may contribute to the problem? And is there anything I can do (diet, exercise, medication, vitamins) that MIGHT help improve my odds? A nutritionist confirms I'm eating near perfectly, but maybe an increase or decrease in certain foods...? I've already cut out caffeine ENTIRELY for many months!
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