PREGNANCY-BIRTH Messages for August, 2001: Thanks Dr Montgomery: Bencerraf study

Thanks Dr Montgomery: Bencerraf study

From: diane (anonymous@obgyn.net)
Wed, 1 Aug 2001 18:17:44 -0500 (CDT)

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You may think this funny but actually I spent most of my discertation/post-doc on statitistical mechanics as I wrote software to run biomolecular simulations and calculations.

I was right on for the sensitivity and positive predictive value but thinking of some other relationship for the specificity.

Thanks for clearing that up!

At Wed, 1 Aug 2001, Lynn D. Montgomery, MD wrote: >
>At Wed, 1 Aug 2001, diane wrote:
>>
>>Thanks Dr. Montgomerey,
>>
>>(Actually my first semester of PCHEM was terrible but then I had quantum
>>and it seemed so much better. That Thermo stuff is old hat anyway!)
>>
>>I am familiar with that study and those numbers
>>I do have some questions concerning their meaning.
>>Thanks a lot for the references. I will be sure to check
>>them out.
>>What do the terms 'sensitivity', 'specificity'
>>and 'positive predictive value' for using
>>EIF to predict DS really mean here?
>>
>>I thought I figured out the first and last but then the second
>>does not make sense to me.
>
>*Come come now, a PhD and no statistics. The sensitivity refers to its
>ability to predict Down's, the specificity predicts the ability to
>differentiate Down's over other processes and the predictive value
>refers to how affectively the finding of an EIF predicts a Down's
>syndrome baby by itself. In other words, the positive predictive value
>for EIF and Down's pretty much sucks...
>Lynn
>
>--
>Lynn D. Montgomery, MD
>Director, Maternal-Fetal Medicine
>Rocky Mountain Perinatal Center
>Missoula, Montana
>
>**Note: Opinions expressed here are for educational purposes only and, as such, do not constitute a physician-patient relationship. This information is not intended to supplant the need for you to consult with your physician prior to choosing therapeutic options and/or interventions.
>
>**Private e-mails cannot be entertained due to time constraints, consequently no private e-mails will receive a response.
>
>**Thank you for your understanding ;-)
>

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