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Re: Plaquenil in pregnancy--another question Dr. Montgomery
From: Amy (anonymous@obgyn.net)
Wed, 18 Apr 2001 15:48:39 -0500 (CDT)
Thank you for your insights. Do you have the citations for the studies
that showed the problems with the Plaquenil? I did a medline search and
all the articles I saw said that there were no reported problems.
Also, since I want to start ttc in the six months and plaquenil has a
long half life. Should I discuss other alternatives with my
rheumatologist? In other words, should I discontinue plaquenil before
ttc?
>
>With regard to the SLE, I tend to favor prednisone. Plaquenil is
>certainly used in pregnancy, but there are reporte anomalies that seem
>related to drug-primarily retinal and neurodevelopmental. If a patient
>is not responding to prednisone, I will consider its use. In your case,
>if you voiced and signed an understanding as to its potential, it could
>be used as a primary.
>
>With regard to waiting, it depends upon whether or not you have any
>end-organ involvement secondary to your lupus (i.e. renal, hepatic,
>etc.). If you do not have any significant impairment, then the waiting
>period is not a necessity and does not predict badly for your lupus
>behavior during the next pregnancy...
>Lynn
>
>--
>Lynn D. Montgomery, MD
>Director, Maternal-Fetal Medicine
>Rocky Mountain Perinatal Center
>Missoula, Montana
>
>**Note: Opinions expressed here are for educational purposes only and, as such, do not constitute a physician-patient relationship. This information is not intended to supplant the need for you to consult with your physician prior to choosing therapeutic options and/or interventions.
>
>**Private e-mails cannot be entertained due to time constraints, consequently no private e-mails will receive a response.
>
>**Thank you for your understanding ;-)
>
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