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Looking for input on Rh disease/antibody titer values

From: Catherine (anonymous@obgyn.net)
Wed, 28 Feb 2001 17:25:58 -0600 (CST)


I am 25 wks pregnant with my third child. I am Rh negative and have received Rhogam at 28 wks and after birth with my 2 previous pregnancies, but somehow I became sensitized after my last pregnancy. My titers were 1:8 for anti-c and 1:16 for anti-D at 11 wks gestation. At 22 wks gestation they were 1:8 for anti-c and 1:32 for anti-D. My doctor does not seem to be concerned with the numbers at this point. I have found many articles on the subject on the web and although they vary in what they call the "critical" titer, it seems to me that I should at least be referred to a perinatologist at this point for a consultation. Some of the articles I found quoted a titer of 1:16 for anti-D as a point where amniocentesis would be the next step, others used 1:32. Currently, I am scheduled for another blood draw at 28 wks, along with an ultrasound. Is this time frame too long? After all the research I did, I called and talked to my doctor about my concerns and he told me he would call and talk to a perinatologist about my case, but I haven't heard back from him. Should we be treating this more aggressively? I'm very concerned that I don't know the condition of my baby - from what I've read, there are no other reliable tests to determine the fetus' condition except for amniocentesis and cordocentesis. I certainly don't want to have invasive testing done if it isn't necessary, but I believe that in my case, it IS necessary. Any input you can give me would be greatly appreciated. Thank you for your time!



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