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Re: Crohns disease... correct spelling is Purinethol or 6MP

From: Kim (anonymous@obgyn.net)
Sun, 18 Feb 2001 09:50:49 -0600 (CST)

At Sun, 18 Feb 2001, Vera, wrote: >
>Dear Kim,
>
>Purinethol inhibits the purine metabolism, which is needed for the DNA
>formation. So, it DOES affects the fertility. Additionally, it has a
>teratogenic effect (harmful for fetus).
>
>--
>Vera, S.Ked.
>Sixth-year medical student in Diponegoro University
>

Do you have any statistical information on the fertility effects. I know I can't take this drug during pregnancy but was never given any info. on the fertility issue!! That concerns me!!! Could you explain purine metabolism in simple terms????

thanks Kim



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