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Re: new drug docosanol and valtrex

From: Lynn D. Montgomery, MD (anonymous@obgyn.net)
Wed, 20 Dec 2000 22:44:10 -0600 (CST)


At Wed, 20 Dec 2000, Lisa wrote: >
>I have posted before about the use of valtrex during my pregnancy. I am
>now 26 weeks along. A month ago, my doctor prescribed valtrex when I
>had a large lesion very near my eye. It was a little too late to take
>the meds at that point, so I did not. She read to me some new research
>about the use of valtrex in all trimesters not just in the last month as
>all the previous posts talk about. She tried to assure me of its
>safety, which is not the message I get on this board. I was wondering
>where I could read this information myself, as taking the drug would be
>wonderful, but I am still very leary because of your comments here.
>Also, the approval of the new Abreva over-the-counter could not be found
>in my doctors drug manual or research. Do you have any information on
>its use during pregnancy?

There is not as much experience with Valtrex as there is with its predecessor Zovirax. There is much experience with zovirax, a lot of it gained in patients that are HIV positive and require supression for that reason. I can't really point you to a specific publication because most of my evidence comes form my colleagues who care primarily for women who are HIV positive and pregnant, particularly Hunter Hamill in Houston, who has been using Zovirax in his patients for several years without a problem. Further, there are several studies in the literature discussing the option of using supression with Zovirax in patients with a history of herpes, from 36 weeks through delivery. All of this data is applicable to Valtrex, basically being the same class of drug... Lynn

--
Lynn D. Montgomery, MD
Director, Maternal-Fetal Medicine
Rocky Mountain Perinatal Center
Missoula, Montana

**Note: Opinions expressed here are for educational purposes only and, as such, do not constitute a physician-patient relationship. This information is not intended to supplant the need for you to consult with your physician prior to choosing therapeutic options and/or interventions.

**Private e-mails cannot be entertained due to time constraints, consequently no private e-mails will receive a response.

**Thank you for your understanding ;-)




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