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not aligned balanced translocationFrom: Christine (anonymous@obgyn.net)Wed, 20 Dec 2000 18:05:38 -0600 (CST)
My husband and I have miscarried twice in the past 6 months. We now have gotten genetic information back and they said that his chromosomes 3 and 5 are translocated. One arm of three changed places with one arm of 5. They are calling this condition a "not aligned balanced translocation". Could anyone shed light on what exactly this means. We have an appointment with a genetic counselor but are really trying to get by until then. One doctor has told us we have about a 50% chance of miscarrying with each pregnancy. He did not mention any possibility of increased rates of physical or mental disabilities however several internet sites have talked about the increased posibilities of severe disabilities and malformations if it can even be carried to term and the chance that the child will carry the gene as well if he/she does survive. Any information you have would be greatly appreciated as we are just trying to handle this mentally one day at a time. As always thank you for helping us understand. Even when we don't like what we hear we are thankful to you doctors who can make things more clear.
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