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Progesterone in 2nd Trimester

From: Alison (anonymous@obgyn.net)
Thu, 9 Nov 2000 16:14:56 -0600 (CST)


I am the one whose progesterone went from 19.45 at 4 1/2 wks to 0.6 at 6 1/2 weeks. I suspect I had an undiagnosed endocrine problem prior to conception, likely an adrenal or pituitary tumor. The endocrinologist that tested me (prior to conception) found nothing at that time but my recent history has had elevated cortisol levels, proteinuria, rapid heart rate, galactorhea (sp?) & change in body shape from pear to apple. (why is always fruit?) My point, my symptoms come and go. I can have +4 protein one day and negative the next.

The progesterone deficiency was treated with 400mg suppositories qid. My levels have hovered around 30. I was diagnosed with gestational diabetes at 9 1/2 wks. I am now 14 wks and on insulin (15 units R/10 units NPH daily). They have me reduced to one 400mg progesterone suppository a day.

My concern is the endocrinologist seems to think the low progesterone means nothing and my OB is feeling that as long as the placenta is there it will take over and that progesterone is unecessary past the 1st trimester.

In my limited understanding, progesterone is still very important in the second trimester. Why else would our bodies be producing it?

What should I do? I just need to know, is progesterone still important?

Thank you, Alison




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