PREGNANCY-BIRTH Messages for September, 2000: Re: Sulfasalazine and Jaundice/Fleet Enemas

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Re: Sulfasalazine and Jaundice/Fleet Enemas
From: R. Daniel Braun, MD (anonymous@obgyn.net)
Sat, 30 Sep 2000 14:42:51 -0500 (CDT)

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In reply to: Diane: "Sulfasalazine and Jaundice/Fleet Enemas"

At Sat, 30 Sep 2000, Diane wrote: >
>I posted a question about Sulfasalazine on Sept. 27 and it was
>mentioned that my baby could be born jaundiced. What effects will that
>have on him? Also, because of my ulcerative colitis I may have to have a
>sigmoidoscopy. What will the effects of Fleet Enemas have on uterine
>contractions?
>
>Thanks!
>
>--
>Diane
>

It doesn't CAUSE jaundice. If the baby has jaundice, the percent of FREE bilirubin, will be higher. THis is because the sulfa combines with the same binding site on albumin that bilirubin does. So if the sulfa is there, then the bilirubin can't and remains free and unbound in the serum.
Unless labor is going to start in a few hours any way, castor oil, fleets, etc. should not do anything at all except cause diarrhea and cramps of the colon.
RDB

-- R. Daniel Braun, MD FACOG FOG
This is for educational purposes only, and is not intended to be replacement or substitute for consultation and examination by an appropriate medical professional. Due to time constraints, private e-mails cannot be answered.

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