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Re: Anti-E and AmniocentesisFrom: Amanda (anonymous@obgyn.net)Fri, 14 Jul 2000 00:42:23 -0500 (CDT)
At Thu, 13 Jul 2000, Steve wrote: > >My wife has tested positive for Anti-E antibodies. Her maternal >screening has also come back positive. Are there significant additional >risk factors, for getting an amnio, because of the Anti-E? So far, my >wifes blood titers have shown acceptable levels of the E antibody. We're >concerned that the amnio may cause the E antibody levels to rise, due to >the possibility of blood mixing. We understand that there is no >equivalent to Rhogam (sp??) for the E antibody. She is about 17 - 18 >weeks along. > >Thanks in advance. I don't *think* that having the amount of blood that *may* mix during the amnio would have any affect on your wife's titers. Also, even if the antibody titers are high, that doesn't mean that the baby is being affected as badly. I myself have the anti-D antibody present (the kind you would normally prevent with Rhogam), and the last titer count was very high at 1:256. That was over 3 months ago, and I'm 35 weeks along now. I've been having amnios done every few weeks since week 24 to determine the effect that the sensitization may have on the baby. Even though my titers are high, the amniotic billirubin levels have decreased to the point that they are in the mid to low Zone 1. -Amanda
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