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Re: Anti-E-Amy
From: R. Daniel Braun, MD (anonymous@obgyn.net)
Fri, 30 Jun 2000 08:22:32 -0500 (CDT)
The rh system of antigens contains 5 antigens: C,D,E,c, and e. D is the
one that is considered rh Positive, absence of D is rh negative. A
person can be EE, or Ee, or ee. In the same way they can also be DD, or
_D, or __ . And likewise they can also be CC, Cc, or cc. As a rule the
c's and the e's (Big and little) don't cause a problem, but when someone
gets sensitized it can cause serious problems. It doesn't matter if one
is sensitized by transfusion or pregnancy, there can still be a problem
with a future sensitized pregnancy. A test can be done to tell if the
FOB(Father Of Baby) is EE, Ee, or ee. If he is ee, then there is no
problem unless there is also an e antibody(not likely because if there
is an E antibody Mom is ee and she wouldn't form an antibody to e. If
he is EE, then the baby will be Ee and a problem could exist. If he is
Ee, there is a 50-50 chance that the baby is either ee or Ee. and hence
a fifty% chance of no problem.
Now is everybody confused?
RDB
At Thu, 29 Jun 2000, chris wrote:
>
>At Thu, 29 Jun 2000, Amy wrote:
>>
>>Chris,
>>my lab was just testing routinly and they found very small traces of
>>this antibody quite by accident. I sure am glad they did, I have to
>>have and amneo next week and Im sure everything will be fine. I did get
>>this from my last pregnancy because my husband carries this, I don't
>>think I am RH neg no one said anything to me about my RH so Im just
>>assuming that all is fine there. If you read the comments the doctor
>>wrote to me she says the same thing. Any how thanks for your response.
>>Amy.
>>
>>>Hi Amy:
>>>
>I was wrong, apparently they do antibody screens on all pregnant women
>now, and according to Dr. Braun. always did where he was. I know they
>didn't do them where I worked, but that was unusual I guess. Anyway,
>that's how your antibody must have been detected, through one of these
>routine screens. As you say, you have not been told you are RH neg and
>you would know by now!
>
>One way to tell if you got sensitized through your first pregnancy would
>be to test your first baby for big E. If positive, then that pregnancy
>would be when it happened because if it happened from the transfusion an
>antibody screen would probably have picked it up during the first
>pregnancy. However, if your first baby is E neg, then it was the
>transfusion. Even though your husband carries big E, the baby could
>still be big E neg, unless your husband has a rare RH type. This
>doesn't really matter though, just curiosity. :<)
>
>I hope everything goes well for you and your baby!
>
>Chris S.
--
R.Daniel Braun, MD FACOG FOG
**Note: Opinions expressed here are for educational purposes only
and, as such, do not constitute a physician-patient relationship.
This information is not intended to supplant the need for you to
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**Thank you for your understanding ;-)
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