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Re: AFP testing From: Kelly Shanahan, MD (anonymous@obgyn.net) Sat, 6 May 2000 00:03:16 -0500 (CDT) Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Kelly Shanahan, MD: "Re: IUI Timing with LH surge" Previous message: Kelly Shanahan, MD: "Re: Xanax and Pregnancy" In reply to: Alesha: "AFP testing" At Fri, 5 May 2000, Alesha wrote: > >Can a Dr. give me some statistics on the testing. As far as when a >test comes back with a positive result for a birth defect, when further >testing is done, how many of those positive results resulted in a birth >defect? There is about a 3-4% false positive rate, meaning the results suggest an abnormality when everything is really okay. The incidence of neural tube defects (indicated by a high AFP) in the US is aobut 1:1000. The incidence of Down's syndrom, whre the AFP is low, depends on maternal age. In my experience, the vast majority of abnrmal results are due to problems with dating -- an ultrasound is done, dates are off and when the AFP is recalculated, the results are normal. Do you recommend the test to all of your patients? Just curious. We offer it to everyone, and give both written and verbal information, but do not make any recommendations one way or the other -- it is up to the parents to decide if they want the test or not. -- M. Kelly Shanahan, MD, FACOG S. Lake Tahoe, CA Replies are for educational purposes only and do not construe a doctor-patient relationship; they do not take the place of a face-to-face consultation with your own doctor. PRIVATE E-MAILS WILL NOT BE ANSWERED! My daughter deserves some of my very limited free time! Next message: Kelly Shanahan, MD: "Re: IUI Timing with LH surge" Previous message: Kelly Shanahan, MD: "Re: Xanax and Pregnancy" In reply to: Alesha: "AFP testing"

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