PREGNANCY-BIRTH Messages for February, 2000: Re: Blood antibodies B & C

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Re: Blood antibodies B & C

From: anonymous@obgyn.net
Wed, 16 Feb 2000 16:07:03 -0600 (CST)

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At Wed, 16 Feb 2000, Amanda wrote: >
>I am 13 weeks pregnant with my second child and have A- blood. My first
>child has A+ blood, and my husband (father of both pregnancies) has O+
>blood.
>
>I was informed by my OB's office that I have tested positive for a small
>amount of B & C antibodies in my blood. She said that it will have to
>be monitored every 4 weeks with an antibody titer. Apparently this
>occurs in about every 1 in 100 pregnancies.
>
>I am aware of the Rh positive and negative antibody in the blood. I
>received a Rhogam injection both at 28 weeks and after delivery of my
>first child.
>
>Do any of the doctors or anyone else have any more information on this?
>
>Thanks!
>
>--
>Amanda
>

There are literally dozens of blood factors that make our blood unique. The ABO and Rh systems are merely the most important. Anti-C antibodies are a part of the CDE system, and have the potential to cause mild to moderate hemolytic disease. I am not familiar with anti-B antibodies, nor could I find any mention of them in a quick perusal of the standard texts.

The issue is whether or not the baby has C antigen or not. If the baby does not have C antigen, then there is no problem. If the baby does have C antigen in its blood, then there is a possibility that your antibodies could begin to attack the baby's blood, destroying the blood to a greater or lesser extent, leaving the baby anemic to a greater or lesser degree. Close monitoring will be essential, as it is possible to treat this condition successfully, if the baby is effected.

--
William D. McIntosh, MD, FACOG
Clarksville, TN

This is for educational purposes only, and is not intended to be replacement
or substitute for consultation and examination by an appropriate medical
professional.  Due to time constraints, private e-mails cannot be answered.

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