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Re: Any *lean* women taking Metformin?From: anonymous (anonymous@obgyn.net)Tue, 19 Aug 2003 15:16:10 -0500 (CDT)
At Tue, 19 Aug 2003, anonymous wrote: > >>I'm surprised that they won't prescribe metformin for PCOS in Europe. Metformin originated in Europe and had been used there for many years (for diabetes) before the FDA in the U.S. finally approved it. But if they in fact won't prescribe metformin and you have to go on injectables it may work. It worked for me when my endocrinologist refused to put me on metformin because I was thin and not-insulin resistant. On the other hand, even if the endocrinologist doesn't have experience using metformin but is willing to try it, you might want to consider that. It really isn't rocket science. There are several new studies that came out in the last year or two that he can look up for further help. You just want to start low and slow to minimize the side effects. So you may start at 500mg with breakfast for 1 week, then when side effects go away increase to 500mg with breakfast and dinner for at least 1 week or longer if needed to decrease the side effects, and then if you can tolerate it go up to 500mg with breakfast, lunch, and dinner. It might take a month or more to get to this dose. Good luck. > >Hi, thanks a lot for your reply. I'll try to answer your questions. I >only ovulated once with 100 mg Clomid, and in that cycle I get my >periods also. Other than that, I needed duphaston to have my cycles. I >always had USs during all my Clomid treatments. My LH/FSH and every >other things are normal, only DHEA-s which is also in the noraml range >but a little high. I do not use any Clomid or anything for a while, and >this month we'll se if I get my period by my own or not. Then I am >thinking to go on injectables. I have seen a lot of endo also, at the >end of the day, what they say is, I am not a typical PCOS even if I am >PCOS. But, there is no longitudinal study done about PCOS, so I might >be in the very early stages, the only way to know that is to wait. And >If I want a baby (which I want terribly), there is no question, the >things that I have to do are the same with or without PCOS. They say >that because prescribing metformine is not done in Europe, and I >couldn't find any endo which was willing to prescribe it to me. One >would do it if I insisted too much, but the thing is he did not have any >experience in treating PCOS with metformine, so how can I trust him? > >Sometimes, having have to wait to see how things will progress (worsen I >mean) just kills me. I wish I knew it now! > >Thanks again,
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