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Re: Any *lean* women taking Metformin?

From: anonymous (anonymous@obgyn.net)
Tue, 19 Aug 2003 09:33:10 -0500 (CDT)


>
>You are not alone in your frustration over your body. I think it would
>definitely help if you had some answers which you do not at this point.
>I will first say that you probably should not try to lose any weight at
>this point. For women with PCOS who are overweight, they need to lose
>weight to help the insulin resistance but if you truly have a BMI around
>18.5, that is probably not necessary. In terms of your diagnosis, you
>can have polycystic ovaries without having PCOS, and vice versa. The
>fact that you had regular periods at one point in your life and have not
>other symptoms makes the diagnosis a little questionable but not
>impossible. Have you had a period with Clomid? How long has all this
>been going on (when did you quit smoking?)?Did you ever have an US while
>on Clomid to see if any follicles are developing (ovulating)and what
>your uterine lining looks like? If you are currently being treated by an
>OB/GYN, you might want to see an endocrinologist for a more thorough
>workup. Again, if you have PCOS you might need metformin to help you
>ovulate but if you do not have PCOS then you need a diagnosis. Stress
>can certainly cause our menstrual cycles to go out of whack but there
>may be something else that is doing it as well that can be treated.
>
>In terms of the injectables, if you have to go that route, I found that
>I had less symptoms than with Clomid. Less moody. But again more
>hyperstimulation.
>
>Hypothalamic amenorrhea is usually diagnosed by blood tests which show a
>low estrogen level and low FSH and LH. Again there are many causes
>including low body fat, anorexia, excessive exercise, stress, and also
>pituitary problems. When was the last time you had a full panel of labs
>done, including prolactin, estrogen, testosterone, thyroid, FSH, LH,
>etc?

Hi, thanks a lot for your reply. I'll try to answer your questions. I only ovulated once with 100 mg Clomid, and in that cycle I get my periods also. Other than that, I needed duphaston to have my cycles. I always had USs during all my Clomid treatments. My LH/FSH and every other things are normal, only DHEA-s which is also in the noraml range but a little high. I do not use any Clomid or anything for a while, and this month we'll se if I get my period by my own or not. Then I am thinking to go on injectables. I have seen a lot of endo also, at the end of the day, what they say is, I am not a typical PCOS even if I am PCOS. But, there is no longitudinal study done about PCOS, so I might be in the very early stages, the only way to know that is to wait. And If I want a baby (which I want terribly), there is no question, the things that I have to do are the same with or without PCOS. They say that because prescribing metformine is not done in Europe, and I couldn't find any endo which was willing to prescribe it to me. One would do it if I insisted too much, but the thing is he did not have any experience in treating PCOS with metformine, so how can I trust him?

Sometimes, having have to wait to see how things will progress (worsen I mean) just kills me. I wish I knew it now!

Thanks again,




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