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Re: Side Affects

From: Angie (anonymous@obgyn.net)
Fri, 15 Aug 2003 23:34:54 -0500 (CDT)


Hi, I too have been diagnosed with PCOS and hypothyroidism. I have been diagnosed with PCOS for several years and have gone through all of the infertility treatments and was successful with two pregnancies. I was then put on Glucophage/Metformin for PCOS. I had pretty good success and felt better. My hair thickened up, the facial hair slowed a little, I was able to lose a few pounds, etc. In February, I started gaining weight again, even though I am basically not eating much. I have gained 15 pounds, started losing my hair again, been so fatigued I can hardly go. I finally went to my regular MD who found out my B12 is low and I have hypothyroidism. I am having thyroid scan next week, and then will start meds. I am wondering if I will go back to my previous weight after I start the synthroid meds. Does anyone know? I am so depressed because I was working to hard to lose the weight I did. My best friend has lost 25 pounds dieting with me, and I gained 15! It is so depressing. I was doing weight watchers until all of this fatigue started. I guess I am just feeling sorry for myself. I have noticed that since I have been on the Glucophage/Metformin, I have started sweating more and feel hotter a lot. I am not sure at this point if my symptoms are PCOS or hypothyroidism. My periods had returned until the first of this year. I am assuming the Glucophage was not effective anymore because of the development of hypothyroidsm. I also developed endometrial hyperplasia in Jan and had a D&C. I feel like I am falling apart. Thanks for letting me vent. Angie

At Fri, 15 Aug 2003, Janet wrote: >
>I also am hotter than normal on metformin. Kicking this one around with
>the endo, we are theorizing that the change in my hormone(even for the
>better) might be causing this. Just a theory, she really isnt all that
>sure about why. As for the acne and hair issues, are you trying to get
>pregnant??? If not, you might want to suggest spironolactone to your
>endo. ITs done wonders for my hair and though I dont have an acne
>issue, I have heard that it does good things there as well. You can not
>take spironolactone if you are trying to have a baby or even if there is
>a possiblity of becoming pregnant because of it causing birth defects.
>What spiro does is lower testosterone, and during the initial weeks of
>pregnancy is when the sex organs are being developed. By the time that
>you would realize that you were pregnant, the damage would already be
>done. Most doctors will not let rx spironolactone unless you are on the
>pill or are no longer capable of bearing chinldren. Once you no longer
>take spironolactone, there is no problems as far as becoming pregnant at
>a later time.
>
>--
>Janet Heller
>
>PS: congrats on the weight loss. You didnt menthoin how long you have
>been on metformin but I am so happy it is at least helping you in that
>area. I it has only been brief, you moght see improvement elsewhere
>soon too.
>
>At Fri, 15 Aug 2003, anonymous wrote:
>>
>>I was diagnosed with PCOS and Hypothyroidism in December and have been
>>on Synthroid .15 for the thyroid and Metformin 2000MG for PCOS since
>>then. My thyroid levels are now normal. My periods started right away
>>and I have been having 30-35 day cycles since, I have lost 49 pounds, my
>>hair has improved and I just generally feel better. My hormone levels
>>have improved but still need some improvement
>>Question 1: The acne is still really bad (sometimes even worse than
>>before) and the facial hair is still bad. On my follow-up visits, my
>>endo keeps asking about acne and facial hair and I tell him no
>>improvement. Should the Metformin be helping or do I need to take
>>something to help with hair and acne? (or do I need to give Met some
>>more time? as my Endo keeps telling me) Also what facial cleansers do
>>you all use for acne?
>>Question 2: I have been overweight most of my life and with excess
>>weight comes sweating but it seems that this summer (first summer on
>>meds and 49 pounds lighter) has been particularly bad even though we
>>have been having a fairly mild summer in Virginia. I used to just get a
>>moist face on a hot day now it's like someone dumped a glass of water
>>over my head and my clothes get soaking wet. Could this be from the
>>meds?
>
>--
>Email always welcome
>Janet at JanetHeller@msn.com
>




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