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Re: Any *lean* women taking Metformin?

From: anonymous (anonymous@obgyn.net)
Fri, 15 Aug 2003 04:43:30 -0500 (CDT)


>
>Hi. I would be happy to answer you questions but if you answer my
>questions back I may be able to help you even more.
>
>1)a) I was diagnoses when I was about 17. I was only having a few
>periods a year, had acne and hirsutism but no insulin resistance and
>normal weight.
>b)You need to have a certain amount of fat on your body in order to
>produce enough hormones so you may need to gain more weight. How much
>do you actually weigh and how tall are you? Do you exercise or restrict
>you diet? I am a fitness fanatic and probably exercised my body fat too
>low.
>2)If you in fact need injectable like I did, the side effects vary
>depending on the drug, but they are similar to Clomid in that they do
>put you at risk for hyperstimulation.
>3)I did in fact have to gain almost 4 kilos in order to become a
>candidate for fertility drugs. My body fat was low enough to suppress
>all my hormones so that I had hypothalamic amenorrhea (meaning no
>periods due to shut down of my hypothalamus). Once I gained weight my
>PCOS came back and I was able to start with the drugs to try to
>conceive.
>
>A few questions for you now:
>
>1) Did you ever have normal periods? How were you diagnosed with PCOS?
>Do you have any other symptoms other than no periods?
>2) Do you exercise, restict your diet, or under a lot of stress?
>3)Any other info about your medical history would be helpful.
>
>Hope this helps.

Thank you very much for your quick reply. I always had my periods, almost never missed one, unless I was really stressed. And that only happened twice. My cycles were always long though ~4.5 weeks. 1.5 years ago they started to come 3-5-3-5-3-5 weeks of intervals. I was in a lot of stress (preparing for my PhD defence) I thought it was because of that. But they continued like that and all of a sudden they stopped, and I kind a spotted for 3 months. Then I went to see a gyno and my US showed polycystic ovaries. I wanted to have children and am alredy 33 so they started Clomid immediately, and since then my body never is left in itself, only this month and i had very light period, almost spotting. Yes, I eat always small, since my childhood I was always very very thin, I try to sport whenever it is possible and I am concerned about my weight. My BMI is ~18.5, it was even less before I quit smoking (but I was at least having my periods back than!). Apart from the US I don't have any other signs of PCOS. My DHEAs is a little high but it is still in the normal range. Last few months during Clomid I even gained 3-4 kilos but it didn't help with my ovulation at all. It only put me in a lot of extra stress. Since my diagnosis I hate my body, I KNOW that this is not my fault, but I don't FEEL that way. Sorry, this is turning into a venting mail. I am thinking: since gaining weight did not help me maybe loosing a little and going back to my normal! (smoking) weight could be the solution. May be being underweight is a good thing for PCOSers. What would you think? About the injectables. Do they make you as moody as Clomid, or may be even more. I was really depressed when I was taking Clomid, will it be more with the injectables? One last question, how do they diagnose hypothalamic amonerrhea?

I am really greatful to you, and again thank you very much for your help. This means a lot to me.




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