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Re: Pregnant - should I continue use of Metformin or go on Insulin?

From: anonymous@obgyn.net
Thu, 07 Aug 2003 21:41:36 +0000


My RE recommended I stay on Metformin for the 1st trimester of pregnancy. I'm now at 13 weeks and was taken off the medication at 12 weeks. Last time, I was taken of Metformin when I found out I was preg and miscarried at 10 wks. My current RE says Metformin can help prevent early miscarriage. And, I've been told that they know that babies whose mothers are on Metformin for the entire pregnancy do not have birth defects, however they do not know if there are any long term effects of the medication on the child - there just have not been enough case studies yet.

Good Luck! > Hi Roxanne,
>
> If you do a search on keywords: "metformin pregnancy safety" you will
> come up with lots of articles. When I was pregnant before, my
> endocrinologist then had put me on Insulin. Had a 2nd trimester loss,
> probably nothing to do with the drugs themselves.
>
> My current endo advised me to go on insulin when i get pregnant. Also
> the chief of obstetrics at Stanford also advised the same. However my
> high risk OB said ultimately its my choice.
>
> Anna
>
> At Thu, 7 Aug 2003, Gray, wrote:
> >
> >What articles? All I've read has said that taking the Metformin into
> >the 2nd trimester increases the chances of a healthy delivery. Did I
> >miss something?
> >-------------------------
> >Subject: Pregnant - should I continue use of Metformin or go on
> >-------------------------
> >-------------------------
> >-------------------------
> >Insulin?
> >-------------------------
> >Message-ID: <200308061921.h76JLdF16795@dns.obgyn.net>
> >-------------------------
> >
> >-------------------------
> >Doctors and Ladies,
> >
> >I had a positive HPT and scheduled to go into do bloodwork in a day or
> >two.

> >I've been taking Metformin for 3-4 months as I'm insulin resistant.
> >Had higher blood glucose levels in my last pregnancy which ended in
> >fetal demise at 21 weeks. At that time I was taking insulin. TO
> >regulate my glucose levels after D&E, endo put me on Metformin 500mg,
> >3
> >times a day.
> >
> >Now I am having difficulty making the choice of staying on Metformin
> >(which is definitely less stressful than being on insulin) and seems
> >the
> >logical choice because I am producing enough insulin but utilization
> >is
> >not happening.
> >However after coming across so many articles on the safety of the
> >drug,
> >I am unsure. Doctor's and fellow PCOSers Please help!!!
> >
> >Thanks,
> >Anna
>




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