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Re: Is METFORMIN worth it????? - lactic acidosis

From: anonymous@obgyn.net
Sat, 29 Mar 2003 18:01:03 -0600 (CST)


At Tue, 27 Feb 2001, amy wrote: >
>just wanted to say that the only time i've heard of someone dying from
>lactic acidosis was on _a few good men_.
>
>i've been on met for 1.5 years and the benefits definitely outweigh the
>negatives (being the diarrhea for the first few days). just ease into
>it gradually.
>
>it has helped me lose weight and my periods are close to regular now as
>compared to only haveing 5-7 a year before.
>
>Alicia, GO FOR IT!
>
>At Tue, 27 Feb 2001, Tracy wrote:
>>
>>>1. DOES MET CAUSE WEIGHT GAIN? I am in the midhigh 400s I think and I
>>>cannot afford anything that can cause even an iota of weight gain.<
>>
>>I never gained weight on either glucophage or glucophage XR. As a
>>matter of fact, I lose weight on this medication as it totally kills my
>>appetite. Actos increased my appetite and I had to really watch my
>>portions on it.
>>
>>>2. CAN THIS DRUG MAKE ME A DIABETIC if I am not and if my sugars have
>>>come down. My fasting blood glucoses used to be borderline 120s, since
>>>weight loss I am down to 101, 99....around there. I am scared of having
>>>this go the opposite way...<
>>
>>Glucophage is an insulin sensitizer. What it does, like Actos and
>>Avandia, is to make the insulin your body produces work better. One can
>>be "insulin resistant" and not diabetic. In fact if you are even
>>slightly insulin resistant, the insulin sensitizing drugs can delay the
>>onset of type 2 diabetes. You should not have a "low" on glucophage. I
>>have had like a total of 4 hypoglycemic episodes on the medication, and
>>all from missing a meal. If you eat regularly you should not have any
>>lows. Not to say lows cannot happen on this drug, they are just not
>>very common if you eat properly and monitor your blood glucose. If you
>>are on ANY drug that affects insulin or blood glucose, you have to have
>>a home monitor and check your blood glucose levels. Especially if you
>>are prone to swings in glucose level.
>>
>>>3. HOW RARE is that one weird disease acidisois lactos----cant spell
>>>it, hopefully youll all know what I mean. ...I think I have it spelled
>>>wrong this rare side effect. Does it kill you immediately? can they
>>>treat it if it happens. I am afraid of "rare" things happening to me. <
>>
>>Well, I was on the glucophage standard formula for over 2 years and have
>>been on Actos for almost a year. I get tested for the side effects 4X a
>>year and never have had a problem. My diabetes endo. and my
>>reproductive endo. have neither seen a case of this side effect.
>>
>>>4. ANYONE BEEN ON THIS DRUG AND HATED IT?<
>>
>>Hated the HELL out of Glucophage! Any dose over 500 mg was utter gut
>>wrenching MISERY! 500 mg got to be like a continuous mild case of food
>>poisoning. Cramps and diarrhea all day long.
>>
>>>5. ANYONE BEEN ON THIS DRUG AND LIKED IT?<
>>
>>Glucophage XR (extended release formula) 500 mg. has caused nary a
>>twinge in the month I have been on it. Actos caused absolutely no side
>>effects either, but was cost-prohibitive in the long term. I reccomend
>>the XR formula, it is gentler to the digestive tract and the gradual
>>release of medication works better if you tend to have frequent lows in
>>blood glucose.
>>
>>>6. CAN ONE MIX ALDACTONE AND METFORMIN> I LOVE MY ALDACTONE AND WELL IM
>>GOING TO BE ON BOTH<
>>
>>Been on Aldactone and some form of insulin sensitizer (glucophage,
>>actos, glucophage xr) continuously since late '98. No problems
>>whatsoever.
>>
>>Good Luck,
>>Tracy

--
On glucophage xr for diabetes (started med 5 days ago)  Have mild diarrhea and some cramping.What are symptoms of lactic acidosis?



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