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Re: Glucophage (Metformin

From: Penny (anonymous@obgyn.net)
Wed, 15 Jan 2003 22:03:40 -0600 (CST)


Thanks so much Sonnett, this is the most complete & informative response I've gotten here. I feel better about her taking this med now. Your answer is what I would hear, but wanted to make sure. I can tell by reading that this drug has helped many women. Congrats on your pregnancy.

At Wed, 15 Jan 2003, Sonnet wrote: >
>It's not exactly being "researched" as a med for PCOS (Although I
>believe there are still studies going on about it,) it's been used to
>treat PCOS for about 10 years now. (I think that was the date on the
>earliest study I saw!) There have been literally hundreds of studies
>showing it's usefulness and safety with PCOS.
>
>As far as effects on the fetus go, it is a "Class B" drug. That means
>that they don't know of any adverse effects on the fetus, but there have
>not yet been any clinical trials on humans to 100% it's safety during
>pregnancy. I *believe* (but I can't remember where I read it so may be
>wrong) that they have conducted tests on animals where they found no
>adverse effects on the fetus. Further, several doctors have recently
>started keeping women with PCOS on met. through a partial or whole
>pregnancy. To my knowledge, even just judging by the women on this
>board, hundreds of women have taken met. during pregnancy and so far
>not a single birth defect has been linked to it. It has also been shown
>in recent years to drastically reduce the miscarriage rate in women with
>PCOS is they stay on it during pregnancy.
>
>I am 9 weeks pregnant after trying for over 3 years, and I am staying on
>my 3g/day of glucophage through the whole pregnancy. I have researched
>this a LOT, and would never stay on it if I thought there was even a
>possibility of harming our baby, after all we went through to get
>pregnant! For me at least, the risk to the baby of my blood sugar and
>mood swings OFF of glucophage was more dangerous than the possible but
>unlikely risks of staying on it.
>
>At Wed, 15 Jan 2003, Penny wrote:
>>
>>My Daughter is due to start on this med. next week. I have been
>>reading up on it in several places. Reading here tells me this is what
>>she needs but I have also read a medical dictionary that tells me maybe
>>not.
>>I have found that it is not yet approved for pcos patients, it is only
>>being researched. It says that patients have been shown to get pregnant
>>after starting this med., the concern is that they do not know what
>>affect the meds have on the fetus. I guess my question is, have any of
>>you ran accross this issue.
>
>--
>email always welcome: sonnet_fitz@hotmail.com
>




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