Re: Just back from the doc's...questions
From: Krista (anonymous@obgyn.net)
Wed, 20 Nov 2002 18:20:26 -0600 (CST)
Good idea about the research, there are hundreds of meds out there, so
wouldn't worry about that too much. It sounds to me like your NP was
not very well informed about PCOS or diabetes for that matter. My
husband and I have run into that problem more often then not with his
diabetes and with my PCOS. Most of the time we have to know more than
the docs, can't tell you how many times they have prescribed an
antibotic for Clay(husband) and its soomething that he will have a sever
hypo or hyperglycemic reation too.
At Tue, 19 Nov 2002, Jenn wrote:
>
>It IS great to talk about all this, huh?!
>Nope, no worries on that front, it's just that my nurse practitioner (who I
>informed about PCOS) talked to some docs who only use Met/Gluc for their
>patients who are trying to conceive because they told my NP "eventually the
>pancreas will stop working if on Glucophage for too long". That's what
>started all of my questions. To me, your explanation that the body would
>build up a tolerance to it makes more sense than them saying the pancreas
>"decides" it's easier to let Mr. Glucophage do it's work. That just doesn't
>make sense. What you're saying does make me nervous, to be honest. If the
>Gluc stops working for all of us with PCOS....what then? I think I'll call
>Bristol-Squibb tomorrow and see if there's any research on this. I haven't
>been able to find anything on medscape.
>--Jenn
>
>>>----- Original Message -----
>From: "Krista" <anonymous@obgyn.net>
>To: "Multiple recipients of list PCOS" <anonymous@obgyn.net>
>Sent: Tuesday, November 19, 2002 3:40 PM
>Subject: Re: Just back from the doc's...questions
>
>> Glad to help, it is so nice to be able to talk to others who are going
>> through the same thing. I have never heard of a doc saying that someone
>> who is IR built up a tolerance to meds, I could be wrong but the whole
>> point from my understanding of being on the meds is to prevent
>> developing diabetes of course with the help of diet and exercise. If
>> your doctor is worried about damage to heart or kidneys has he put you
>> on an ace inhibitar (sp?) the ADA actually has recommended that
>> diabetics are given an ace inhibitar (blood pressure meds) to prevent
>> damage?
>>
>> At Tue, 19 Nov 2002, Jenn wrote:
>> >
>> >VERY interesting. Ok--here's my next question...If the diabetic body
>builds
>> >up a tolerance to oral meds, what about someone who isn't diabetic. This
>is
>> >where I think the controversy is. Since we (some PCOS women) aren't
>diabetic
>> >(yet) does the "intolerance principle" apply to us? This isn't something
>> >I've heard applied to IR maybe because the damage isn't as bad(?). I'd
>love
>> >to hear from some women out there who have been on Gluc. for a long
>period
>> >of time...if there are any.
>> >Thanks, again, Krista...you have been a great source of info!
>> >--Jenn
>> >
>
>>>> >>----- Original Message -----
>> >From: "Krista" <bafish@tampabay.rr.com>
>> >To: "Multiple recipients of list PCOS" <pcos@mail.medispecialty.com>
>> >Sent: Tuesday, November 19, 2002 3:07 PM
>> >Subject: Re: Just back from the doc's...questions
>> >
>> >> At Thu, 14 Nov 2002, Jenn wrote:
>> >> >The meds will eventually stop working because your body builds a
>> >tolerance, when you are a type I or II diabetic you can go through what
>is
>> >called a Honeymoon phase, your body may respond to the medications for a
>> >short tiime, but then your pancress will no longer respond, and the docs
>> >scramble to change or increase your meds. If the met or glucaphage stop
>> >working there are many other drugs that can be tried, usually insulin
>shots
>> >are a last resort. The American Diabetic Association has just recently
>> >increassed the age limits for a type I diabetic to the early to mid 40's
>so
>> >there is always a chance that the oral meds will stop working completely
>and
>> >no choice but to take injections. My husband was dx with diabetes just
>> >after he turned 20, about 11 years ago, and went through the honeymoon
>phase
>> >for about 9 months of oral meds, which only worked for 2 weeks, before
>the
>> >doctors were willing to dx as type I, as back then the age limit was late
>> >teens early 20's as a maximum.!
>> >> The good news now is that they are in FDA trials to test an insulin
>> >patch, so no injections. So long story short (or am I too late for that!
>> >:-)) your body simply builds an intolerance to the meds. Hope this
>helps!
>> >>
>> >> >Ok..that's the way I understood it. BUT these doctors told my NP that
>> >using
>> >> >Met/Gluc. over long periods of time will cause the pancreas to shut
>down.
>> >> >Sounds like the key is diet and exercise to help the drug help us.
>> >> >Everything can be so confusing. I have almost stopped listening to
>> >anything
>> >> >but the most recent studies but then again, those can change too! This
>> >> >sucks.
>> >> >--Jenn (nif)
>> >> >THANKS KRISTA!!
>> >> >PS. Do you have any info on WHY Met/Gluc stops working...I had never
>> >heard
>> >> >this before.
>> >> >
>> >
>
>>>> >>> >>----- Original Message -----
>> >> >From: "Krista" <bafish@tampabay.rr.com>
>> >> >To: "Multiple recipients of list PCOS" <pcos@mail.medispecialty.com>
>> >> >Sent: Thursday, November 14, 2002 4:54 PM
>> >> >Subject: Re: Just back from the doc's...questions
>> >> >
>> >> >> Hi just wanted to let you know what I know about metforin and other
>> >> >> diabetic drugs being used to treat PCOS. The drugs help your body
>to
>> >> >> use the insulin that your body makes. Eventually the medications
>will
>> >> >> not work as effectively and IR will turn in to type II diabetis
>which
>> >> >> may or may not require an injection of insulin. Current research
>shows
>> >> >> that with diet and exercise type II diabeties can be prevented and
>the
>> >> >> meds will continue to help with the IR. My husband is a type I
>> >> >> diabetic, so we currently receive all kinds of literature about
>> >> >> diabeties and now the new classification of IR. If you go to the
>> >> >> American Diabetic Associations web site there is all kinds of
>> >> >> information to help understand the new IR classification and PCOS in
>> >> >> relation to insulin. Hope this helps.
>> >> >>
>> >> >> At Thu, 14 Nov 2002, jodi wrote:
>> >> >> >
>> >> >> >It doesn't make any sense to me. If anything it should save the
>> >> >> >pancreas. The reason IR can lead to Type II diabetes is because
>> >> >> >eventually the pancreas just poops out.
>> >> >> >
>> >> >> >There are a lot of doctors who won't prescribe met for various
>> >reasons.
>> >> >> >My opinion is these docs are either ignorant or just think PCOS is
>not
>> >> >> >anything to worry about... or both.
>> >> >> >
>> >> >> >There have been a LOT of studies showing met helps women with PCOS.
>> >WHat
>> >> >> >happens over the long term, though, I think has yet to be
>established.
>> >> >> >(IE does it stop working after a while, are there long term health
>> >> >> >risks...)
>> >> >> >
>> >> >> >- jodi
>> >> >> >
>> >> >> >At Thu, 14 Nov 2002, Jenn wrote:
>> >> >> >>
>> >> >> >>Me too...I thought it helped the body utilize he insulin it
>> >> >makes....that's
>> >> >> >>why I'm confused. Apparently these doctor's theory is that the
>> >pancreas
>> >> >will
>> >> >> >>shut down because it isn't being used enough (?). Does that make
>any
>> >> >sense
>> >> >> >>to anyone???
>> >> >> >>--Jenn (nif)
>> >> >> >>PS. Thanks Sally :-)
>> >> >> >>
>> >> >>
>> >> >> --
>> >> >> Krista
>> >> >> Dover Florida
>> >> >> dx 8 years
>> >> >>
>> >>
>> >> --
>> >> Krista
>> >>
>>
>> --
>> Krista
>> Dover Florida
>> dx 8 years
>>
--
Krista
Dover Florida
dx 8 years
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