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Re: ANDROCUR USERS!!! PLEASE READ!!!From: Barb (anonymous@obgyn.net)Thu, 5 Sep 2002 01:17:02 -0500 (CDT)
In most countries Androcur (cyproterone acetate) can only been prescribed by a medical specialist. Androcur or cyproterone acetate is an anti-androgen which is prescribed to treat androgen dependant conditions. Cyproterone acetate is used for women who have too much androgen production and/or seem to be overly sensitive to androgen activity in their bodies. Cyproterone acetate is used for acne and/or overactive oil glands and hirsutism as well as androgen dependent hair loss. In men, cyproterone acetate is used for prostate cancer treatment, to reduce sex drive in men, for the treatment of sexual aggression, and for use by male to female transsexuals in conjucntion with estrogen supplements. What are the effects of taking Androcur? Androcur is an antiandrogenic hormone preparation. It inhibits the influence of androgens which are also produced - to a slight extent- in the female organism, and also exerts a progestational and antigonadotrophic effect. Cyproterone acetate inhibits competitively the effect of androgens at androgen-dependent target organs, e.g. it shields the prostate from the effect of androgens originating from the gonads and/or the adrenal cortex. In the man, under treatment with ANDROCUR, sexual drive and potency are reduced and gonadal function is inhibited. These changes are reversible following discontinuation of the therapy. In the woman, hirsuitism is reduced, but also androgen-dependent alopecia and elevated sebaceous gland function are reduced. During treatment, ovarian function is reduced. Dosage: The extreme range of dosage comes from input that some people find 10mg/wk sufficient to induce total impotence, and yet others take as much as 200mg/day with no obvious short-term adverse effects. Given this range, it would seem prudent to start on the low side and work your way up only if necessary. More than 100mg/day is generally considered excessive. There are some reports of depression when the dosage is too high for a given individual. There appears to be a causal relationship because the depression evidently disappeared as soon as the dosage was reduced, according to those reports. WARNING: Androcur is the most powerful of anti-androgen drugs and must not be taken by any patient with a medical condition, or one who is taking / has recently taken other drugs that are contra-indicated. During treatment, liver function, adrenocortical function and the red blood-cell count should be checked regularly. Direct hepatic toxicity, including jaundice, hepatitis and hepatic failure, which has been fatal in some cases, has been reported in patients treated with 200 - 300mg cyproterone acetate. Most reported cases are in men with prostatic cancer. Toxicity is dose-related and develops, usually, several months after treatment has begun. Liver function tests should be performed pre-treatment and whenever any symptoms or signs suggestive of hepatotoxicity occur. If hepatotoxicity is confirmed, cyproterone acetate should normally be withdrawn, unless the hepatotoxicity can be explained by another cause, e.g. metastatic disease, in which case cyproterone acetate should be continued only if the perceived benefit outweighs the risk. Hope this information helps. Ask your doctor about it. Personally,I would not increase the dose.In many cases with drugs..less is more. You can sometimes tolerate a drug at a higher dose than at a lower dose and vise versa.Never increase the dosage without consulting your health care provider. Please let us know how you are doing on this medication.
Barb
>From reading on this drug,it has effects on the complaints you have.
>
-- Sincerely, Barb C.
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