PCOS Messages for July, 2002: Re: Am i the odd woman out here??????

Re: Am i the odd woman out here?????? - SHBG

From: anonymous@obgyn.net
Tue, 2 Jul 2002 00:16:16 EDT

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Sorry I didn't see your earlier post. I don't have those symptoms associated with excess testosterone either, like hirsutism, thinning hair, acne etc. I think I have found out why too. A couple of weeks ago I had a number of blood tests done & my sex hormone binding globulin was abnormally high. From the info I have gathered from the Internet and after talking to my GP, as a PCOS sufferer it should be very low. This is what I think happens. SHBG is a ß-globulin that transports testosterone in plasma. Once testosterone binds to the SHBG it is no longer an active hormone. Women with PCOS tend to have elevated levels of free testosterone in their systems because they do not have enough SHBG for the testosterone to bind too. Therefore the testosterone becomes an active hormone, which results in hirsutism, virilizaiton, obesity and diffuse hair loss. Anyway maybe those PCOS sufferers without the above mentioned symptoms all have elevated levels of SHBG. Also low levels of SHBG plays a role in the development of insulin resistance and subsequent type 2 diabetes. There wasn't much talk in the articles I read on how to increase your levels of SHBG, some believe there is a connection between increased fibre intake and high levels of SHBG but all seem to agree increases in estrogens = increases in SHBG. So now I have a quick question (which probably seems very obvious - sorry) but do BCP's contain estrogen? Kirstie Australia

In message dated 02-Jul-02 12:08:40 AM W. Australia Standard Time, anonymous@medispecialty.com writes:

> Hi....i recently posted and there were no responses to my post....i am
> beginning to think that most people have ongoing problems from the mild
> to the severe with pocs....in my case i can honestly say that I dont
> have hair growth, acne, or a lot of problems I have seen on here.....i
> do have weight grain and a lack of a monthly cycle IF I dont take
> BCP's.....i have been on them for years and they keep my cycle
> regulated, I was actually told that there are some serious problems that
> can develop if you dont have a cycle so I chose to take the pill.....i
> have been put on metformin, clomid, prevarin, all of those made me sick
> and i could not take any of them.....from nausea to turning into someone
> with horns, no luck on any of them....i also have perodic back pain....
>
> from someone just trying to figure this out
>
.. >

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