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From: Belle (anonymous@obgyn.net)
Tue, 26 Feb 2002 20:58:03 -0600 (CST)


First thing you should do is go to http://www.pcosupport.org and learn about PCOS. It is a great resource.

If you do have your PCOS under control, your IVF will be more likely to work.

Glucophage is a drug that you have to work up to. There is no medal that you get for putting up with the side effects. Start out slowly. If you can take 500 mg without problems, cut a pill in half and try 750 mg for a week then go up to 1000 mg. If you cannot take 750 mg, cut the pill in quarters and try that for a week. Go up as slowly as necessary until you reach your theraputic level.

Take the pill with your largest meal of the day. When you begin taking the second pill, take it with your next largest meal of the day. Try taking the pill before meals, after meals, in the middle of meals to see what works best. Try not to eat high carb meals, this can make things worse for some.

Are you sure you had high FSH and low LH? This is different from what we usually see with PCOS.

Glucpohage has been very good at helping women ovulate, combined with Clomid, the success rate has been even higher. For women with PCOS, taking Glucophage during the first few months of pregnancy has been shown to reduce the likelyhood of a miscarriage (a big problem for us).

At Tue, 26 Feb 2002, Lori wrote: >
>I've recently been diagnosed with PCOS, although I don't really
>understand the diagnosis. My husband and I have just started the IVF
>process, we start injections in about a week. My infertility doctor put
>me on Glucophage, he wants me to take 1500mg/day, so far I've only been
>able to take 1000mg. I'm wanting to find out if anyone has experienced
>similar difficulty with this drug and can help me control the side
>effects. My tests supposedly showed that I have high FSH and low LH, I
>don't really have a problem with blood sugar or insulin. My regular
>doctor says my case is very mild, I don't have cysts and I ovulate
>regularly. My problem is that I am EXTREMELY nauseous, ALL DAY!! I
>can't get over it. It doesn't matter what I eat or if I eat all day,
>I'm still nauseous. They've told me to eat a high protein diet but I'm
>so sick that meat or cheese or eggs or nuts are the last thing I want to
>eat and when I try it's all I can do not to gag. Any help would be
>great. I've talked to the doctor and this is the treatment they want to
>keep me on and if IVF works I'll have to stay on it through the entire
>pregnancy so I just have to learn to control the effects of it. Please
>help!
>
>Thanks.

--
Hope this helps,

Belle




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