PCOS Messages for December, 2001: Re: PCOS and no IR?

Re: PCOS and no IR?

From: Belle (anonymous@obgyn.net)
Sat, 29 Dec 2001 19:45:37 -0600 (CST)

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Reply: Missy: "To Belle: PCOS and no IR?"

You can be thin and have PCOS. You can be thin and have IR. Fasting glucose means nothing. 199mg/dl is not normal. 200mg/dl is diabetic. Between 140 and 199 mg/dl is considered Glucose Intolerant. Fasting levels should be less than 120 mg/dl but ideally between 60 - 80mg/dl for a 8 - 12 hour fast. None-the-less, this does not have anything to do with insulin. A fasting insulin may help detect if you are IR but more likely, it will take a 2 hour Glucose Tolerance test with insulin levels (IGTT)to help make that determination.

The truth of the matter is that doctors who are involved in PCOS research seem to feel that all women with PCOS would have IR if the tests were sensitive enough to detect it. The IGTT can only help diagnose IR because it is really only test for hyperinsulinemia. The actual test for insulin resistance is not done on women because of the costs. These are only done on research projects.

Only about 1/2 of the women with PCOS are overweight according to some reports. IR can have nothing to do with weight. My daughter was always considered thin by her pediatricians to the point that this was commented on several times. When she started her period and did not regulate after a year, I took her in to the endo who did a a 2-hour IGTT on her and guess what? Extremely thin, hard to put on weight and ... diagnosed IR.

At Sat, 29 Dec 2001, Missy wrote: >
>I am not overweight nor do I have a
>problem controlling my weight but I still wonder if I have PCOS, but how
>could I if I am probably not IR?
>
>I read that only 10% of non-overweight women with PCOS have IR so how
>does one explain PCOS in them? What caused it?
>
>My fasting glucose level was 77 with 65-199mg/dl being the normal range.
>Does that mean anything? thanks, missy

-- Hope this helps,

Belle

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