Re: D-CHIRO-INOSITOL --buckwheat bran?
From: Celeste (anonymous@obgyn.net)
Thu, 13 Dec 2001 14:55:12 -0600 (CST)
At Wed, 12 Dec 2001, cat wrote:
>
Hi Cat, I am not good at bookmarking links, but I can tell you where I
found out most of the info I have. It is on http://www.soulcysters.com. The
lead researcher is Dr. John Nestler, and all of his PCOS research
papers are links on that site. Also he is the lead researcher for the
drug company Insmed, and their site has a little info at http://www.insmed.com.
The actual drug name is INS-1.
At http://www.centerwatch.com you can find out about clinical trials for
d-chiro; be sure to look under PCOS, endocrine disorders, women's
health, and ob/gyn to make sure you have found all possible ways it can
be listed; also you may have to do some emailing because they don't
always mention *which* drug they are testing--it could be Met, Avandia,
Actos, etc. When you enter a clinical trial you have a 50% chance of
getting the drug or not. I came very close to getting into a study on
it locally (there were delays in getting the medication from the
manufacturer and since you have to be off all meds prior to the start, I
couldn't live with my symptoms any longer and bowed out). They gave me
plenty of information on it at the trial clinic. They had already done
some trials there and it was fascinating to hear how well the stuff
worked on the ladies who got. Ovulation resumed and they felt a million
times better; it was not a magic weight loss pill but "normal" methods
of weight loss seemed to work a whole lot better.
The folks at http://www.minndak.com are marketing the d-chiro aspect of
farinetta buckwheat bran as healthful in ways beyond PCOS treatment, but
they will send you a huge supply for free if you want to try it. They
suggest adding it to hot cereal, pancakes, chili, shakes, and baking
flours. However any of these are too carby for me since I follow Atkins
lowcarb dieting, and the product only added more carbs to it.
I have Dr. Nestler's email address at home if you would want that; he
is very friendly and answers emails, but he truly does not believe you
can adjust diet to replace d-chiro. I think he really wants to help,
and I also believe that sometimes holistic measures just aren't enough
and some of us really do NEED medication. Good luck and email me
anytime if you want to chat.
>Hi Celeste, I am really interested in d-chiro, do you have any links to
>the latest research about it?
>
>Thanks very much,
>Cat
>
>At Wed, 12 Dec 2001, Celeste wrote:
>>
>>At Wed, 12 Dec 2001, tricia wrote:
>>>
>>This may not be what you want to hear, but it's roughly impossible for
>>us to eat enough D-chiro containing foods daily to replace our
>>deficiency. The latest research shows that PCOS womens' bodies dump out
>>d-chiro into our urine FIVES TIMES FASTER than normal women do. They
>>still don't understand the mechanism for why we begin to dump it out,
>>but it is supposedly the loss of it in the chain that makes our insulin
>>go too high and cause the cascade of symptoms we know as PCOS.
>>
>>The inositol tablets are made from brown rice powder and I have never
>>talked to anyone who thought they helped. Soy lecithin capsules or
>>granules are the most concentrated and lowcarb source of d-chiro in
>>food, but as pointed out, you still would need to take a big handful of
>>them every day and no one has ever reported that it actually helped,
>>only that this substance contains a lot of the chemical. Unfortunately
>>not many foods contain this naturally and the ones that do have it in
>>low levels so you would have to eat FAR more than you could stand every
>>day to try to get the benefits.
>>
>>There is a buckwheat bran called farinetta you can get from
>>http://www.minndak.com which studies show is high in d-chiro-inositol, but the
>>fact is that it is very high in carbohydrate and those of us (like me)
>>who don't respond to Met alone usually find that carbohydrate
>>restriction is very helpful. I got the most help to resume cycles,
>>lower testosterone, lose weight, and ovulate by lowcarbing to lose
>>weight and using Met plus Avandia. I really wanted diet and exercise to
>>be enough for me, but my testosterone stayed high and Avandia really
>>changed all that. I'm almost halfway through a pregnancy and doing
>>great. But I still want to try the d-chiro-inositol drug when it comes
>>out!!!!!
>>
>>>Just wanted to let you know that you can buy inositol in plain form. The
>>>tablets are huge, but you only have to take 2 a day. I found them at my
>>>local grocery store. I also found them online. Have been taking them
>>>about 2 weeks, haven't noticed any difference, but I also didn't respond
>>>to the metformin. Good luck.
>>> At Sun, 2 Dec 2001, anonymous@obgyn.net wrote:
>>>>
>>>>I purchased some soy lecithin capsules. Once I figured out how much
>>>>lecithin I had to take in order to get my 1,200 mgs/day of
>>>>d-chiro-inositol, I realized why they're coming out with a pill. I'd
>>>>basically need to take a large bottle a day of lecithin capsules, and
>>>>there's no way I could afford that.
>>>>
>>>>I took several capsules a day for a long time and never noticed any
>>>>difference.
>>>>
>>>>However, considering PCOS women are low in d-chiro-inositol, it sure
>>>>can't hurt to eat lots of foods high in it.
>>>>
>>>>Lisa
>>>
>>>--
>>>tricia
>>>
>>--
>>Celeste
>>
--
Celeste
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