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Re: aaagh! confusion over how hormones + insulin all affect each otherFrom: Sonnet (anonymous@obgyn.net)Tue, 11 Dec 2001 00:41:46 -0600 (CST)
Anne, this is another clip from that article: "Based upon the available data at this time, it appears that in some women, androgen disorders start out as an abnormality in adrenal function. The adrenal gland produces increased amounts of androgen either at puberty or at some time later in life due to significant stress. The adrenal gland produces increased androgen if the woman has been born with one of the adrenal enzyme deficiencies. In some women the problem remains isolated to the adrenal gland. These women show clinical evidence of increased androgen production with hirsutism and/or acne but they often do not show any alteration in menstrual function and are often normally fertile. In other women, the increased adrenal androgens affect the normal growth of the follicles in the ovary. They prevent the eggs from developing normally and halt the growth of the follicle. As I have pointed out, under these circumstances, the egg dies and the follicle is no longer able to produce adequate amounts of estrogen but does continue to produce significant amounts of androgen. Therefore, by the time the woman appears in the office for evaluation, she no longer has a simple adrenal problem nor does she have a purely ovarian disorder. Rather, she has a combined problem with increased androgen production from both the ovary and the adrenal and, if she is overweight, with a substantial contribution from her body fat." It's basically saying that in some women, although the IR is a major part of the PCOS, it can start as a problem with the adrenals producing too much male hormone. I think :)
At Mon, 10 Dec 2001, anne wrote:
>
-- Sonnet Fitzgerald, PCOS Association, Online Community Liaison. Email: sonnet@pcosupport.org
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