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Re: aaagh! confusion over how hormones + insulin all affect each otherFrom: anne (anonymous@obgyn.net)Sun, 9 Dec 2001 21:39:22 -0600 (CST)
Thanks a lot Sonnet. Could you post the link for the article? I'd LOVE some indepth information on this. BTW I'm so pleased to hear about your son-to-be - that's great news! At Sun, 9 Dec 2001, Sonnet wrote: > >I've got a great link for you, if you've got time to read through it: > >It is VERY long, and at times it can get a LITLLE technical although >oveall it's very well written and easy to understand without any >scientific background. It's just that our endocrine system is so >complex, even the basics of it are enough to make your head spin! > >That article goes through a lot of the hormonal process in PCOS, in the >ovary and aside from it. This clip is a great, short overview of PCOS >and it points out the pathological process clearly putting the ovaries >in their place as a tissue affected by PCOS, not the cause. (Although >it also reminds us that not ovulating / PCO makes everything worse.) > >"If a teenage girl is overweight, is insulin resistant, and has >inherited the trait that predisposes her to abnormal ovarian/adrenal >function, the stage is then set for her to develop PCOS. The increased >insulin resistance results in elevated serum insulin levels which then >stimulates excess androgen production. This results in evidence of >excess androgen production with facial hirsutism and/or acne. > >The excess androgen may also worsen the obesity, adding fuel to the >fire. > >Increased androgen production interferes in normal ovulation. Women >with this syndrome then stop ovulating (or probably never started in the >first place). The increased androgen production blocks development of >the follicles and so the ovary becomes "polycystic". The abnormal ovary >then begins to produce increased amounts of androgen." > >It's complicated I know! But I do hope this helps! > >-- >Sonnet > >-- >Sonnet Fitzgerald, PCOS Association, Online Community Liaison. Email: sonnet@pcosupport.org >
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