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Re: HELP NEEDED!!! - long replyFrom: SusieQ (anonymous@obgyn.net)Wed, 29 Aug 2001 19:34:28 -0500 (CDT)
I am sorry Celeste, I must respectfully disagree. Metformin is already difficult on the kidneys and adding a low carb regimine is not recommended by most diabetes/pcos specialists. Instead they recommend a National Diabetes Foundation diet. Since my RE specifically told me not to dip below 70 grams of carbs per day while taking Metformin, I hope you will not be offended if I stick with his recommendation. This article outlines a professionals opinion about low carbing (under 50 grams per day): PCOS and DIET by Martha McKittrick, Registered Dietician, Certified Diabetes Educator, OBGYN.net Editorial Advisor, found here: http://www.obgyn.net/pcos/articles/pcos_and_diet_mckittrick.htm. She specifically recommends not to low carb for PCOSers. Metformin is metabolized by the kidneys, and uric acid provides a source for kidney stones in a ketogenic/high protein diet, together they put the kidneys at risk. Our friend Paula has made a comment in support as well here: http://forums.obgyn.net/pcos/PCOS.0009/1384.html. The National Institute of Diabetes & Digestive & Kidney Diseases says: "It overworks your kidneys, and can cause dehydration, headaches, and bad breath. It can also make you feel nauseous, tired, weak, and dizzy. A buildup of ketones in your blood (called ketosis) can cause your body to produce high levels of uric acid, which is a risk factor for gout (a painful swelling of the joints) and kidney stones. Ketosis can be very risky for pregnant women and people with diabetes. By following a reduced-calorie diet that is well-balanced between carbohydrates, proteins, and fats, you will still lose weight--without hurting your body. You will also be more likely to keep the weight off." Found here: http://www.niddk.nih.gov/health/nutrit/pubs/myths/index.htm Researchers are scrutinizing the kidneys need for carbohydrates and their importance in renal function. Another reason not to overwork your kidneys by denying them important carbs. Read the research, Renal Gluconeogenesis Its importance in human glucose homeostasis by John E. Gerich, MD, Christian Meyer, MD, Hans J. Woerle, MD and Michael Stumvoll, MD here: http://care.diabetesjournals.org/cgi/content/abstract/24/2/382?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext=kidney+low+carbohydrate&searchid=999130068467_7=kidney+low+carbohydrate&searchid=999130068467_792&stored_search=&FIRSTINDEX=40 Another research article that implicates low-carb diets can increase "insulin resistence" called, "A possible mechanism of insulin resistance in the rat adipose cell with high-fat/low-carbohydrate feeding. Depletion of intracellular glucose transport systems" by PJ Hissin, E Karnieli, IA Simpson, LB Salans and SW Cushman found here: http://diabetes.diabetesjournals.org/cgi/content/abstract/31/7/589?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext=kidney+low+carbohydrate&searchid=9991309762text=kidney+low+carbohydrate&searchid=999130976263_824&stored_search=&FIRSTINDEX=70 As you can see, I do not agree with low carbing COMBINED with Metformin...this is not an argument, nor an attack. I feel that everyone should have all the information necessary to make the correct decision for themselves. Personally I feel miserable on met and low carbing. I hope everyone taking insulin lowering medications will talk with their doc before starting any diet regimen. All our test results are different, and all our needs are different. Urban Legends are not my cup of tea; double-blind, placebo controlled studies are. Again, Randi, I urge you to talk with your doc about your test results and possible treatment options (including diets).
-- SusieQ
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