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Re: bcps and IR ???
From: Joan (anonymous@obgyn.net)
Wed, 20 Dec 2000 10:03:27 -0600 (CST)
I have heard of this before. The jury still isn't out on BCPs. My
interpretation of what Dr. Thatcher has written about this is as
follows: BCPs are useful for some patients in diminishing syptoms and
they still have a place in treatment. The relationship to IR is
probably not that significant. Hope that helps. If you can't any
positive changes, I would suggest talking to your RE to see if there
have been any positive hormonal effects. Have you tried any insulin
sensitizers?
Joan
At Wed, 20 Dec 2000, k wrote:
>
>Does anyone know anything about this?
>
>I ran across it in my reading.
>It's off of the Trileven site.
>
>I'm kind of worried because I was on bcps for about 8 months and my
>symptoms got worse (facial hair and hair loss)
>
>Went off to try to get my hair back and through blood tests found out I
>have pcos. NOW I'm on Mircette and Aldactone.
>
>I don't think I have IR but wouldn't be suprised if I'm hypoglycemic.
>Those symptoms have actually gotten worse since going on bcps again.
>
>I need to know if I'm doing more harm than good here.
>
>Thanks - K
>
>8. CARBOHYDRATE AND LIPID METABOLIC EFFECTS
>
>Oral contraceptives have been shown to cause glucose intolerance in a
>significant percentage of users. Oral contraceptives containing greater
>than 75 micrograms of estrogens cause hyperinsulinism, while lower doses
>of estrogen cause less glucose intolerance. Progestogens increase
>insulin secretion and create insulin resistance, this effect varying
>with different progestational agents. However, in the nondiabetic
>woman, oral contraceptives appear to have no effect on fasting blood
>glucose. Because of these demonstrated effects, prediabetic and
>diabetic women should be carefully observed while taking oral
>contraceptives.
>
>A small proportion of women will have persistent hypertriglyceridemia
>while on the pill. As discussed earlier (see "WARNINGS" 1a. and 1d.),
>changes in serum triglycerides and lipoprotein levels have been reported
>in oral-contraceptive users.
>
>--
>k
>
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