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Re: Met & Aldactone

From: jane (anonymous@obgyn.net)
Thu, 16 Nov 2000 08:47:00 -0600 (CST)


I had no real side effects when I started taking 100 mg (25mg X 4 times/day) of spironolactone. Yes, I do have to take last dose after 6pm at 11pm which did make me get up to pee once or twice a night..but no gastric related side effects. But when I had been on metformin..even though I did slowly build up dosage during 4 weeks to 2000 mg/day..had nausea, diarhea and stomach cramps most of the whole time for 1st 2 months..So met is the harder drug to adjust to, not the spiro/aldactone...I did stop the met before switching to spiro..but make sure you drink alot of water to prevent dehydration especially more so if you take both drugs at same time.

At Thu, 16 Nov 2000, Jo-Nita wrote: >
>Hi Kris, My endo put me on Aldactone this week and He will have me start
>Met soon, also. I wanted to pass olong the advice he gave me. He
>believes in starting low and increasing your dose of Aldactone slowly.
>He started me out with 25mg. once a day for 1 week, then 50mg. once a
>day for the second week, then 75mg.(2- 25mg in a.m. & 1-25mg. p.m.)
>fot the 3rd week, then 100mg. ( 2-25's a.m. & 2-25's p.m.) for the 4th
>week on. He also suggested that I take the p.m. dose before 6:00,
>since aldactone also acts as a diuretic and he didn't want me to pee all
>night!! My fasting insulin was 34, and so he also wants me to start on
>Met. But not all at once, so since I'm really faithful about my diet
>(low-carb, No sugar, & not much art. sweetner either) he will wait just
>a while before I begin Met. He feels low-carbing, & aldactone, & Met
>are a little tough to throw at your liver all at once. My concern for
>you is that you are starting out on such a high dose of Aldactone. You
>might question your Dr. about a more gradual start. Sometimes there
>are gastric side effects that could be avoided by a slower start to the
>drug therapy.(e.i. nausea, diahrria, upset stomach, etc.) Keep us
>informed on how you do. You are welcome to e-mail me privately if I can
>be of help. Good Luck.
>
>--
>Take Care, Jo-NIta
>




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