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Re: tagamet?belleFrom: anonymous (anonymous@obgyn.net)Wed, 19 Jul 2000 10:49:57 -0500 (CDT)
Belle, I copied the following from planet Rx. This is what worries me. I have been on Met 2000 mg since about february. I am going to call my doctor and ask him about this, but do you have any thoughts about it? sorry if i posted this twice, it did not seem to go thru the first time. thanks for any help. Tagamet interacts with Glucophage Severity: Moderate Description: Cimetidine may significantly reduce the renal tubular secretion of metformin. In one study, the area under the plasma concentration-time curve for metformin was increased by 50% and the plasma clearance was reduced by 27%. Particularly slow and cautious titration of metformin dosage is recommended if these drugs must be used together. The maximal dose of metformin should also be reduced.
At Wed, 19 Jul 2000, Belle wrote:
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