PCOS Messages for May, 2000: Re: inositol questions

Re: inositol questions

From: Avalos (anonymous@obgyn.net)
Wed, 10 May 2000 10:39:31 -0500

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Sallie:

Thank you for that very clear and detailed information. I have been wondering the same thing expressed in Ellen's question, juts never got around to phrasing the question quite right enough to post it...

I do have a follow-up question....

Is there any information about whether people taking d-chiro-inositol or plain inositol can also take Metformin or are they mutually exclusive?

Clara

-----Original Message----- From: anonymous@obgyn.net [mailto:anonymous@obgyn.net Sent: Wednesday, May 10, 2000 11:17 AM To: Multiple recipients of list PCOS Subject: Re: inositol questions

At Tue, 9 May 2000, Ellen wrote: >
>Is d-chiro-inositol (from several med journals) the same as inositol?
>What, if anything, is the difference between them? I understand that
>inositol is an herbal supplement (??) but what is it supposed to do?
>Ellen

Hi Ellen, I have been researching inositol for awhile and asked many "experts" and doctors. I can never get a clear answer on exactly what d chiro inositol is but I believe it is an end form of inositol that the body produces. Inositol has many forms depending on how many phosphates are attached during the metabolic process that inositol takes. In food inositol can be found in two forms - plain inositol which is myo inositol(the kind you would find in supplemental form) and phytic acid which is inositol with all 6 phosphates attached (the most phosphates inositol can gain). It is found in fiber of soy beans, oranges, pine bark, rice(unrefined), and other foods. A person probably injests around 1000mg of inositol every day. Also it is not considered a true vitamin because the body can produce itself. It is always considered as part of B complex group of vitamins because they all work together. It is known that in PCOS and in diabetes that inositol is not metabolized right or maybe it is a inherited tendency to be deficient easily. Diabetics, and I think they are testing to see if women with PCOS, are always deficient in d chiro inositol(or more there is high level of d chiro inositol lost through the urine meaning that the blood or muscle levels do not have what they need). I had always thought it would be useless to take plain inositol until I talked to a woman who had been in a study where they tested 1200mg of plain inositol on an empty stomach for women with PCOS. It made her have regualar periods and raised her progesterone levels considerably. I have given it to my daughters and it has helped them to have regular peroids. If you read everything you can find on inositol you find a trend that it has been known for a long time that diabetics are deficient in inositol and they are cautioned about taking supplemental inositol because it could lower their diabetic medication or insulin requirments. I think that by taking it on an empty stomach inositol is not disrupted or changed by insulin or enzymes and therefore able to complete its metabolic pathway. If I have time this afternoon or tommorow I will type out what is in a very good book on inositol and phytic acid (which is also called IP6[inositol with 6 phosphates attached]. The book is called IP6+inositol.

--
Sallie

Next message: Avalos: "Re: EFA's and Low carb dieting???"
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