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Re: Diagnosed yesterday. Medical questions RE my doctor & met. (Long)Questions about Avandia!

From: A (anonymous@obgyn.net)
Mon, 27 Mar 2000 23:23:00 -0500


My fasting insulin test was also in the normal range. I am planning to ask for the GTT; however, what determines IR when testing the insulin levels & sugar together...that sounds confusing.....what results prove that IR exists?

Ann Marie wrote:

> The fasting insulin test can be useless. I tested in the normal range
> on my fasting insulin test. I was given a test through a study that I'm
> doing and unfortunately I can't remember the name of it. Basically what
> they did was shut down my pancreas and injected me with insulin and
> glucose. They then monitored insulin and glucose levels for several
> hours. At the end my glucose level was still too high which told me
> that I was insulin resistant. Does anyone know the name of the test?
>
> Anyway supposedly the Glucose Tolerance Test (GTT) will also show
> whether you are insulin resistant or not, but you have to make sure that
> they are measuring insulin levels along with sugar levels. I used to be
> with Kaiser and they will do the test but you have to request it.
>
> I'm now with Aetna and might be going on a study with Avandia. Has
> anyone tried Avandia yet?
>
> At Mon, 27 Mar 2000, anonymous@obgyn.net wrote:
> >
> >At Fri, 24 Mar 2000, Belle wrote:
> >>
> >>I am not worried about the dr diagnosing you based on your history,
> >>especialy since bloodwork was ordered. He is correct that blood levels
> >>can be in normal range and you still have problems. Since you asked for
> >>and presumably got an order for the insulin test, this is a good sign.
> >>
> >Hello, my name is Katie and I just came across this list while
> >web-searching about PCOS. I have a couple of simple questions (which
> >were kind of touched on in the archives, but I would like to be sure so
> >I can talk to my Dr. from a solid footing, ya know?)
> >First of all, some history ... I'm 28, have excess facial hair (big
> >nasty black hairs despite the fact that I'm blonde), am overweight and
> >can't seem to lose weight with diet and/or exercise, and my periods have
> >been really irregular for about six years.
> >I finally got around to mentioning these things to my doctor and she
> >thought right away it could be PCOS. But my blood work (reproductive
> >hormones, fasting insulin) was within normal ranges (except cholesterol
> >and triglycerides but my levels of those have always been high). She's
> >sending my for a pelvic/abdominal ultrasound anyway; I go in a week.
> > My questions:
> >1. Are hormone levels always wacky with PCOS, or are there periods (no
> >pun intended) of "normalcy"??
> >2. I suspect (and have for a long time) that I'm insulin resistant.
> >Isn't getting a glucose level after 12 hours of fasting (which is what
> >my test was) kind of useless to detect IR?? I'd like to ask her to test
> >my insulin levels but doctor's kind of intimidate me.
> > Thanks (sorry about length).
> > Katie
>




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