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Re: Glucophage/Metformin non-PCOS pregnancyFrom: anonymous@obgyn.netFri, 12 Sep 2003 10:10:55 -0500 (CDT)
At Tue, 4 Sep 2001, crissy wrote: > >At Mon, 3 Sep 2001, anonymous wrote: >> >>My wife and I have recently become pregnant. On consulting with her OB, >>it was dicovered that while not diabetic, she is insulin resistant (I'll >>cal it IR). >> >>Our OB recommended 1500mg of glucophage/metformin to deal with her IR, >>and it sounds like he wants her to take it for the full term of the >>pregnancy and beyond, until she can stabilize her IR through exercise >>and diet (which we are assuming she can). >> >>We have found snippets of both the Glueck and Hellmuth studies, and are >>bit confused by what the healthiest decisions are for both my wife and >>our baby. >> >>We feel relatively ok with the glucophage through the first trimester >>(but still have questions for the OB), as it should help her with the >>insulin levels, and hopefully give us less of a chance of miscarriage. >>But what about beyond that? The Glueck study is great to hear (and the >>OB seems to be a supporter of the philosophy - his office has been using >>it for PCOS patients for a year now). But for one thing, my wife is not >>a PCOS patient, and the Hellmuth study is a bit frightening with the >>perinatal deaths that occured. >> >>Does anyone have any more information on the use of glucophage during >>pregnancy on someone who is only IR, and NOT a PCOS patient? If >>possible, we would also like to see both of the studies in full. (One >>of my big questions on the Hellmuth study is, what exactly was the cause >>of the perinatal deaths in the subset of glucophage babies - was it the >>same across the board, and can it be traced back to glucophage?). >>Information on any other studies that may have been done would also be >>great. Any help is greatly appreciated! >> >>Thank you! > >Hi I am happy to here about your success, I am afraid i can't help with >your >questions but was curious as to how long your wife has been taking >glucophage/met before becoming pregnant and at what dose? I am also not >diabetic but have an insulin resistance and have been prescribed >glucophage 500 2x a day, >I have been taking it for about 3 weeks now. Did your wife have reg >cyles before taking it? any info you can offer will be helpful as it is >all new to me. I would also be interested in the answers to your >concerns as I will hopefully >be wondering the same soon. Thank you and congratulations! > >-- >Kristine > ------------- I was also prescribed glucophage and I am not a diabetic but have suspected IR. My husband and I are trying to have a child and are currently seeing a Reproductive Endocrinologist because I have a Growth Hormone Defeciency and I am currently taking humatrope for that. I too have questions about taking it during the whole time of pregnancy. Eventhough is has not been 'proven' to be safe the doctor says it should be fine to take it through the entire pregnancy. Any information would be helpful. I would be happy to answer any questions about my condition or experiences I've had so far.
-- ~Theresa in Phoenix.
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