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Re: Initiating Metformin

From: anonymous (anonymous@obgyn.net)
Thu, 28 Aug 2003 17:41:46 -0500 (CDT)


So if I understand correctly all blood work related to insulin and sugar as well as your ultrasound were normal but you still were put on the medication and it helped w/ your weight. Did it help w/ normal phasing of periods? Thank you very much for taking the time to respond. At Wed, 27 Aug 2003, click wrote: >
>I went to my new general practitioner because of my rapid weight gain
>(unexplained; ate very little), my low energy, missed period for mroe
>than a year, etc.. I was 16 years old, 5'7, 240 lbs, blood pressure was
>170/100.
>
>The Dr ordered blood work checking a couple types of testosterone
>levels, sugar levels, lipid levels, and some other items.. after that,
>my GP suspected PCOS--she sent me to a gynocologist & an
>endocronologist. I got into the gyno first. The gyno did an exam as
>I'd never had one before--to check for abnormalities because of my high
>testosterone, and then sent me to have an ultrasound of my ovaries done
>(non vaginal as I was a virgin) to rule out any large cysts or abnormal
>sizing. All that came back OK, but I still haddn't had a period, so my
>gyno put me on high doses of progesterone for 5 days and I had a 30 day
>long period. About two weeks into that, I demanded to start the insulin
>resistance treatment I'd been suspected of having since I haddn't been
>able to get into the endocronologist yet and my weight was getting
>worse, so my gyno perscribed me enough for a month to hold me over. The
>endocronologist had ultrasounds of my kidneys done, a CAT of my adrenal
>glands, etc to rule out any other causes of my symptoms and things that
>would be problems with the medication. Also, my blood pressure after a
>few weeks of the metformin had dropped to 150/90--a large improvement.
>All of the tests came back normal and he continued my glucophage
>treatment and continued communicating with my gynecologist.
>
>Two months later I had realized that the medication's side effect that
>were only to last the adjustment period were still plaguing me and
>really crippling my life (in bed after 5pm because of stomach
>pain/cramps, cold sweats, up and down blood sugar & moods) and so my
>endocronologist switched me to glucophage XR (time release) and it was
>magic. Two months later I'd lost 12 pounds or so, by 6 or 7 months I
>had lost 40 pounds--all without effort--eating the same as I had before
>I was diagnosed (which was not bad, btw, except for soda which was not
>in excess)
>
>... anyway, That's the summed up version of events.
>
>At Wed, 27 Aug 2003, anonymous@obgyn.net wrote:
>>
>>A doctor should take blood to run the following; FSH (Follicle
>>Stimulating Hormone), will be normal or low with PCOS,LH (Lutenizing
>>Hormone), will be elevated with PCOS,LH/FSH greater than 2:1 or 3:1 may
>>be considered diagnostic of PCOS, Prolactin can be normal or low with
>>PCOS ,Testosterone, total and/or free usually elevated with PCOS,DHEAS,
>>frequently mildly elevated with PCOS , Estrogens, may be normal or
>>elevated with PCOS , Lipid profile (low HDL, high LDL, and cholesterol,
>>elevated triglycerides) Glucose, may be elevated, Insulin, often
>>elevated with PCOS ,TSH (Thyroid stimulating hormone) some who have PCOS
>>are also hypothyroid
>>
>>I had the initial blood test that checked most of the above and then I
>>had the glucose tolerance test to rule out diabetes.
>>
>>Also, they did a vaginal Ultrasound to evaluate cysts/enlarged ovaries.
>>
>>Hope this helps.
>>
>>At Tue, 26 Aug 2003, anonymous wrote:
>>>
>>>I'd like to hear from anyone about how their doctor came to place them
>>>on Metformin/glucophase. Was it the results of blood tests, if so which
>>>ones?
>>>Thanks



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